In the initiation or exacerbation of Alzheimer disease, the dissemination of oral
microorganisms into the brain tissue or the low‐level systemic inflammation have been …

Neuroinflammation has either beneficial or detrimental effects, depending on risk factors and
neuron–glia interactions in neurological disorders. However, studying neuroinflammation …

Recent epidemiological studies show a noticeable correlation between chronic microbial
infections and neurological disorders. However, the underlying mechanisms are still not …

Porphyromonas gingivalis (P. gingivalis) is a Gram-negative anaerobic pathogen that is
involved in the pathogenesis of periodontitis and systemic diseases. P. gingivalis has …

Background: Pre-clinical evidence implicates oral bacteria in the pathogenesis of
Alzheimer's disease (AD), while clinical studies show diverse results. Objective: To …

Alzheimer's disease (AD) is the most prevalent form of dementia, characterized by a
progressive cognitive decline. Sporadic AD, accounting for more than 95% of cases, may …

Objective This study investigated the spinal changes in ligature‐induced periodontitis and
the role of periodontitis in cognitive impairment. Methods Twenty mice were randomized into …

Periodontitis and infections with periodontal bacteria have been highlighted as risk factors
for dementia. In recent years, attention has been drawn to the role of microglia cells in …

Background The association between cognitive neurodegenerative disease and oral
diseases has been under great interest recently. Several studies have suggested a …

Neurological disorders in the central nervous system (CNS) are progressive and irreversible
diseases leading to devastating impacts on patients' life as they cause cognitive impairment …