Metformin and cancer: solutions to a real-world evidence failure
OHY Yu, S Suissa - Diabetes care, 2023 - Am Diabetes Assoc
The quest to repurpose metformin, an antidiabetes drug, as an agent for cancer prevention
and treatment, which began in 2005 with an observational study that reported a reduction in …
and treatment, which began in 2005 with an observational study that reported a reduction in …
Identification of Parkinson's disease PACE subtypes and repurposing treatments through integrative analyses of multimodal data
Parkinson's disease (PD) is a serious neurodegenerative disorder marked by significant
clinical and progression heterogeneity. This study aimed at addressing heterogeneity of PD …
clinical and progression heterogeneity. This study aimed at addressing heterogeneity of PD …
Architectural styles of curiosity in global Wikipedia mobile app readership
Intrinsically motivated information seeking is an expression of curiosity believed to be central
to human nature. However, most curiosity research relies on small, Western convenience …
to human nature. However, most curiosity research relies on small, Western convenience …
Exploring the impact mechanism of executives' environmental attention on corporate green transformation: evidence from the textual analysis of Chinese companies' …
X Ding, Z Xu, MV Petrovskaya, K Wu, L Ye… - … Science and Pollution …, 2023 - Springer
The allocation of executives' environmental attention (EEA) is of great significance in
promoting the green upgrading of industrial structures and achieving corporate green …
promoting the green upgrading of industrial structures and achieving corporate green …
Real-world evidence of ocrelizumab-treated relapsing multiple sclerosis cohort shows changes in progression independent of relapse activity mirroring phase 3 trials
J Ingwersen, L Masanneck, M Pawlitzki… - Scientific Reports, 2023 - nature.com
Ocrelizumab is a B cell-depleting drug widely used in relapsing–remitting multiple sclerosis
(RRMS) and primary-progressive MS. In RRMS, it is becoming increasingly apparent that …
(RRMS) and primary-progressive MS. In RRMS, it is becoming increasingly apparent that …
Assessing fairness in machine learning models: A study of racial bias using matched counterparts in mortality prediction for patients with chronic diseases
Objective Existing approaches to fairness evaluation often overlook systematic differences in
the social determinants of health, like demographics and socioeconomics, among …
the social determinants of health, like demographics and socioeconomics, among …
Artificial intelligence-based forensic sex determination of East Asian cadavers from skull morphology
H Kondou, R Morohashi, S Kimura, N Idota… - Scientific Reports, 2023 - nature.com
Identification of unknown cadavers is an important task for forensic scientists. Forensic
scientists attempt to identify skeletal remains based on factors including age, sex, and dental …
scientists attempt to identify skeletal remains based on factors including age, sex, and dental …
The impact mechanism of green credit policy on the sustainability performance of heavily polluting enterprises—based on the perspectives of technological innovation …
X Ding, R **g, K Wu, MV Petrovskaya, Z Li… - International Journal of …, 2022 - mdpi.com
Green credit policy (GCP), as one of the key financial instruments to achieve'carbon
peaking'and 'carbon neutrality'targets, provides capital support for the green development of …
peaking'and 'carbon neutrality'targets, provides capital support for the green development of …
A network-based systems genetics framework identifies pathobiology and drug repurposing in Parkinson's disease
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder.
However, current treatments only manage symptoms and lack the ability to slow or prevent …
However, current treatments only manage symptoms and lack the ability to slow or prevent …
Word2vec word embedding-based artificial intelligence model in the triage of patients with suspected diagnosis of major ischemic stroke: a feasibility study
A Desai, A Zumbo, M Giordano, P Morandini… - International Journal of …, 2022 - mdpi.com
Background: The possible benefits of using semantic language models in the early
diagnosis of major ischemic stroke (MIS) based on artificial intelligence (AI) are still …
diagnosis of major ischemic stroke (MIS) based on artificial intelligence (AI) are still …