Rational design strategies for nanozymes

Z Chen, Y Yu, Y Gao, Z Zhu - ACS nano, 2023 - ACS Publications
Nanozymes constitute an emerging class of nanomaterials with enzyme-like characteristics.
Over the past 15 years, more than 1200 nanozymes have been developed, and they have …

Multienzyme‐like nanozymes: regulation, rational design, and application

J Sheng, Y Wu, H Ding, K Feng, Y Shen… - Advanced …, 2024 - Wiley Online Library
Nanomaterials with more than one enzyme‐like activity are termed multienzymic
nanozymes, and they have received increasing attention in recent years and hold huge …

Biosystem‐inspired engineering of nanozymes for biomedical applications

L Zhang, H Wang, X Qu - Advanced Materials, 2024 - Wiley Online Library
Nanozymes with intrinsic enzyme‐mimicking activities have shown great potential to
become surrogates of natural enzymes in many fields by virtue of their advantages of high …

Nanozymes: A clear definition with fuzzy edges

H Wei, L Gao, K Fan, J Liu, J He, X Qu, S Dong… - Nano Today, 2021 - Elsevier
Recently, an editorial in ACS Catalysis entitled 'nano-apples and orange-zymes' questioned
whether or not the term “nanozyme” was appropriate [1]. When a new term in science is …

MOF-818 nanozyme-based colorimetric and electrochemical dual-mode smartphone sensing platform for in situ detection of H2O2 and H2S released from living cells

K Yu, M Li, H Chai, Q Liu, X Hai, M Tian, L Qu… - Chemical Engineering …, 2023 - Elsevier
Abstract Hydrogen peroxide (H 2 O 2) and hydrogen sulfide (H 2 S) play a key role in many
cellular signaling pathways. The efficient and accurate in situ detection of H 2 O 2 and H 2 S …

Ultra‐Small High‐Entropy Alloy Nanoparticles: Efficient Nanozyme for Enhancing Tumor Photothermal Therapy

Y Ai, MQ He, H Sun, X Jia, L Wu, X Zhang… - Advanced …, 2023 - Wiley Online Library
High‐entropy alloys nanoparticles (HEANPs) are receiving extensive attention due to their
broad compositional tunability and unlimited potential in bioapplication. However …

Nanozyme-enabled analytical chemistry

S Li, Y Zhang, Q Wang, A Lin, H Wei - Analytical Chemistry, 2021 - ACS Publications
In 2007, landmark research recognized ferromagnetic nanoparticles (Fe3O4 NPs) as the
substitute of horseradish peroxidase (HRP) for their alike catalytic ability to oxidize signal …

Atomic-level design of metalloenzyme-like active pockets in metal–organic frameworks for bioinspired catalysis

W Xu, Y Wu, W Gu, D Du, Y Lin, C Zhu - Chemical Society Reviews, 2024 - pubs.rsc.org
Natural metalloenzymes with astonishing reaction activity and specificity underpin essential
life transformations. Nevertheless, enzymes only operate under mild conditions to keep …

Reaction mechanisms and kinetics of nanozymes: insights from theory and computation

X Shen, Z Wang, XJ Gao, X Gao - Advanced Materials, 2024 - Wiley Online Library
Abstract “Nanozymes” usually refers to inorganic nanomaterials with enzyme‐like catalytic
activities. The research into nanozymes is one of the hot topics on the horizon of …

Nitrogen‐enriched conjugated polymer enabled metal‐free carbon nanozymes with efficient oxidase‐like activity

D Zhu, M Zhang, L Pu, P Gai, F Li - Small, 2022 - Wiley Online Library
Metal‐free carbon nanozymes could be promising with the unique features of intrinsic
catalytic ability, structure diversity, and strong tolerance to acidic/alkaline media. However, to …