Increasing evidence suggests that abnormal cerebral glucose metabolism is largely present
in Alzheimer's disease (AD). The brain utilizes glucose as its main energy source and a …

Hippocampal volume increase in response to aerobic exercise has been consistently
observed in animal models. However, the evidence from human studies is equivocal. We …

Cognitive dysfunction is often reported in patients with post-coronavirus disease 2019
(COVID-19) syndrome, but its underlying mechanisms are not completely understood …

Brain cells normally respond adaptively to bioenergetic challenges resulting from ongoing
activity in neuronal circuits, and from environmental energetic stressors such as food …

Alzheimer's disease (AD) and type 2 diabetes (T2D) are both diseases with increasing
prevalence in aging populations. T2D, characterized by insulin resistance and defective …

Recently researchers proposed the term 'Type-3-Diabetes' for Alzheimer's disease (ad)
because of the shared molecular and cellular features among Type-1-Diabetes, Type-2 …

Mitochondria are associated with various cellular activities critical to homeostasis,
particularly in the nervous system. The plastic architecture of the mitochondrial network and …

Immune cells react to their environment by flexibly reprogramming intracellular metabolic
pathways that subsequently alter immune function, in a process called immunometabolism …

Vascular insults can initiate a cascade of molecular events leading to neurodegeneration,
cognitive impairment, and dementia. Here, we review the cellular and molecular …

The age-associated decline of the neurological and cognitive functions becomes more and
more serious challenge for the developed countries with the increasing number of aged …