Water solubility and structural stability are key merits for proteins defined by the primary
sequence and 3D-conformation. Their manipulation represents important aspects of the …

Heat-triggered drug release from temperature-sensitive nanocarriers upon the application of
mild hyperthermia is a promising approach to achieve site-specific delivery of drugs. The …

The successful design of a hydrogel for tissue engineering requires a profound
understanding of its constituents' structural and molecular properties, as well as the proper …

With almost 20 million new cases per year, cancer constitutes one of the most important
challenges for public health systems. Unlike traditional chemotherapy, targeted anti-cancer …

Injectable nanocarriers and hydrogels have found widespread use in a variety of biomedical
applications such as local and sustained biotherapeutic cargo delivery, and as cell …

Self-assembling proteins are valuable building blocks for constructing drug nanocarriers
due to their self-assembly behavior, monodispersity, biocompatibility, and biodegradability …

The efficacy and specificity of conventional monoclonal antibody (mAb) drugs in the clinic
require further improvement. Currently, the development and application of novel antibody …

Coiled-coil protein motifs have become widely employed in the design of biomaterials.
Some of these designs have been studied for use in drug delivery due to the unique ability …

The fields of precision imaging and drug delivery have revealed a number of tools to
improve target specificity and increase efficacy in diagnosing and treating disease …

Extensive research has gone into deciphering the sequence requirements for peptides to
fold into coiled-coils of varying oligomeric states. More recently, additional signals have …