COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

Insights for COVID-19 in 2023

FJM Sánchez, M Martínez-Sellés… - Revista Española …, 2022 - pmc.ncbi.nlm.nih.gov
Predictions for a near end of the pandemic by the World Health Organization should be
interpreted with caution. Current evidence indicates that the efficacy of a fourth dose of …

Nirmatrelvir use and severe Covid-19 outcomes during the Omicron surge

R Arbel, Y Wolff Sagy, M Hoshen, E Battat… - … England Journal of …, 2022 - Mass Medical Soc
Background The oral protease inhibitor nirmatrelvir has shown substantial efficacy in high-
risk, unvaccinated patients infected with the B. 1.617. 2 (delta) variant of severe acute …

[HTML][HTML] Effectiveness of a bivalent mRNA vaccine booster dose to prevent severe COVID-19 outcomes: a retrospective cohort study

R Arbel, A Peretz, R Sergienko, M Friger… - The Lancet Infectious …, 2023 - thelancet.com
Background In late 2022, the SARS-CoV-2 omicron (B. 1.1. 529) BA. 5 sublineage
accounted for most of the sequenced viral genomes worldwide. Bivalent mRNA vaccines …

Neutralizing antibody activity against 21 SARS-CoV-2 variants in older adults vaccinated with BNT162b2

J Newman, N Thakur, TP Peacock, D Bialy… - Nature …, 2022 - nature.com
SARS-CoV-2 variants may threaten the effectiveness of vaccines and antivirals to mitigate
serious COVID-19 disease. This is of most concern in clinically vulnerable groups such as …

Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old: A nationwide …

P Nordström, M Ballin, A Nordström - The Lancet Regional Health …, 2022 - thelancet.com
Background The effect of a fourth dose of COVID-19 vaccine on the risk of death in the
oldest and frailest individuals is unknown. Methods Two matched cohorts were formed using …

Expert review of global real-world data on COVID-19 vaccine booster effectiveness and safety during the omicron-dominant phase of the pandemic

R Solante, C Alvarez-Moreno, E Burhan… - Expert review of …, 2023 - Taylor & Francis
Introduction COVID-19 vaccines have been highly effective in reducing morbidity and
mortality during the pandemic. However, the emergence of the Omicron variant and …

COVID-19: From emerging variants to vaccination

TH Senevirathne, D Wekking, JWR Swain… - Cytokine & Growth …, 2024 - Elsevier
The vigorous spread of SARS-CoV-2 resulted in the rapid infection of millions of people
worldwide and devastation of not only public healthcare, but also social, educational, and …

Immunogenicity and efficacy of fourth BNT162b2 and mRNA1273 COVID-19 vaccine doses; three months follow-up

M Canetti, N Barda, M Gilboa, V Indenbaum… - Nature …, 2022 - nature.com
Booster doses for the ongoing COVID-19 pandemic are under consideration in many
countries. We report a three-month follow-up of 700 participants in a fourth vaccine dose …

Association of receiving a fourth dose of the BNT162b vaccine with SARS-CoV-2 infection among health care workers in Israel

MJ Cohen, Y Oster, AE Moses, A Spitzer… - JAMA Network …, 2022 - jamanetwork.com
Importance Despite the high 3-dose vaccination rate among health care workers (HCWs) in
Israel, a high rate of SARS-CoV-2 breakthrough infections in this group was observed during …