Voltage-gated calcium channels are required for many key functions in the body. In this
review, the different subtypes of voltage-gated calcium channels are described and their …

Voltage-gated calcium (Ca2+) channels are key transducers of membrane potential
changes into intracellular Ca2+ transients that initiate many physiological events. There are …

▪ Abstract Voltage-gated Ca2+ channels mediate Ca2+ entry into cells in response to
membrane depolarization. Electrophysiological studies reveal different Ca2+ currents …

A polymorphic CAG repeat was identified in the human α1A voltage-dependent calcium
channel subunit. To test the hypothesis that expansion of this CAG repeat could be the …

Voltage-gated calcium channels are the primary mediators of depolarization-induced
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …

Injury to or disease of the nervous system can invoke chronic and sometimes intractable
neuropathic pain. Many parallel, interdependent, and time-dependent processes, including …

Ion channels are membrane proteins that act as gated pathways for the movement of ions
across cell membranes. They play essential roles in the physiology of all cells. In recent …

Voltage-gated calcium (Ca 2+) channels initiate release of neurotransmitters at synapses,
and regulation of presynaptic Ca 2+ channels has a powerful influence on synaptic strength …

The physical distance between presynaptic Ca2+ channels and the Ca2+ sensors that
trigger exocytosis of neurotransmitter-containing vesicles is a key determinant of the …

Mutations at the mouse tottering (tg) locus cause a delayed-onset, recessive neurological
disorder resulting in ataxia, motor seizures, and behavioral absence seizures resembling …