Comparison of conventional and advanced in vitro models in the toxicity testing of nanoparticles

E Fröhlich - Artificial cells, nanomedicine, and biotechnology, 2018 - Taylor & Francis
Humans are exposed to a wide variety of nanoparticles (NPs) present in the environment, in
consumer, health and medical products, and in food. Conventional cytotoxicity testing …

Molecular dynamics simulation strategies for designing carbon-nanotube-based targeted drug delivery

MN Al-Qattan, PK Deb, RK Tekade - Drug discovery today, 2018 - Elsevier
Highlights•CNT-based target-specific drug delivery is a promising approach to circumvent
the limitations of nonspecific therapeutic agents.•Interactions between the drug, CNT and …

Short-Term Intravenous Administration of Carbon Nano-Onions is Non-Toxic in Female Mice

YZ Tan, LR Thomsen, N Shrestha… - International Journal …, 2023 - Taylor & Francis
Background A nanoscale drug carrier could have a variety of therapeutic and diagnostic
uses provided that the carrier is biocompatible in vivo. Carbon nano-onions (CNOs) have …

Nanoparticulate drug delivery strategies to address intestinal cytochrome P450 CYP3A4 metabolism towards personalized medicine

RX Zhang, K Dong, Z Wang, R Miao, W Lu, XY Wu - Pharmaceutics, 2021 - mdpi.com
Drug dosing in clinical practice, which determines optimal efficacy, toxicity or ineffectiveness,
is critical to patients' outcomes. However, many orally administered therapeutic drugs are …

Photoluminescent semiconducting graphene nanoribbons via longitudinally unzip** single-walled carbon nanotubes

H Li, J Zhang, AB Gholizadeh… - … Applied Materials & …, 2021 - ACS Publications
The lack of a sizeable band gap has so far prevented graphene from building effective
electronic and optoelectronic devices despite its numerous exceptional properties. Intensive …

Exploring the Nanotoxicology of MoS2: A Study on the Interaction of MoS2 Nanoflakes and K+ Channels

Z Gu, LD Plant, XY Meng, JM Perez-Aguilar, Z Wang… - ACS …, 2018 - ACS Publications
Molybdenum disulfide (MoS2) nanomaterial has recently found various applications in the
biomedical field mainly due to its outstanding physicochemical properties. However, little is …

Applying in silico approaches to nanotoxicology: Current status and future potential

NL von Ranke, RB Geraldo, AL dos Santos… - Computational …, 2022 - Elsevier
Nanomaterial development is one of the most significant technological advances of the 21st
century, with considerable impact in several fields. However, nanomaterials can pose risks …

Improved biomedical properties of polydopamine-coated carbon nanotubes

S Demirci, M Sahiner, SS Suner, N Sahiner - Micromachines, 2021 - mdpi.com
Carbon nanotubes (CNTs) due to their outstanding mechanical, thermal, chemical, and
optical properties were utilized as a base material and were coated with polydopamine …

Observation of defect density dependent elastic modulus of graphene

H Li, E Gürbüz, S Haldar, T Hussain, X Zheng… - Applied Physics …, 2023 - pubs.aip.org
The recent decade has witnessed a tremendous development of graphene applications in
many fields; however, as one of the key considerations, the mechanical properties of …

Cytochrome P450 2D6 biosensor for perphenazine based on multi-walled carbon nanotube/ionic liquid and tetrathiafulvalene-tetracyanoquinodimethane salt/ionic …

T Shu, J Wang, X Li, X Wang, S Wang - Electrochimica Acta, 2023 - Elsevier
Abstract A cytochrome P450 2D6 (CYP2D6) biosensor was developed with the
incorporation of multi-walled carbon nanotube/ionic liquid and tetrathiafulvalene …