NF-κB signaling in macrophages: dynamics, crosstalk, and signal integration

MG Dorrington, IDC Fraser - Frontiers in immunology, 2019 - frontiersin.org
The nuclear factor-κB (NF-κB) signaling pathway is one of the best understood immune-
related pathways thanks to almost four decades of intense research. NF-κB signaling is …

Cell type-specific roles of NF-κB linking inflammation and thrombosis

M Mussbacher, M Salzmann, C Brostjan… - Frontiers in …, 2019 - frontiersin.org
The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

Valorization of pomelo (Citrus grandis Osbeck) peel: A review of current utilization, phytochemistry, bioactivities, and mechanisms of action

R Tocmo, J Pena‐Fronteras… - … Reviews in Food …, 2020 - Wiley Online Library
Citrus grandis Osbeck, commonly known as “pomelo” or “shaddock,” is the largest citrus fruit,
the peel of which is a well‐known agricultural residual waste. Pomelo peel offers a wide …

NF-κB in immunobiology

MS Hayden, S Ghosh - Cell research, 2011 - nature.com
NF-κB was first discovered and characterized 25 years ago as a key regulator of inducible
gene expression in the immune system. Thus, it is not surprising that the clearest biological …

Lipid mediator class switching during acute inflammation: signals in resolution

BD Levy, CB Clish, B Schmidt, K Gronert… - Nature …, 2001 - nature.com
Abstract Leukotrienes (LTs) and prostaglandins (PGs) amplify acute inflammation, whereas
lipoxins (LXs) have unique anti-inflammatory actions. Temporal analyses of these …

NF-κB and the immune response

MS Hayden, AP West, S Ghosh - Oncogene, 2006 - nature.com
One of the primary physiological roles of nuclear factor-kappa B (NF-κB) is in the immune
system. In particular, NF-κB family members control the transcription of cytokines and …

[HTML][HTML] Neutrophils: molecules, functions and pathophysiological aspects

V Witko-Sarsat, P Rieu, B Descamps-Latscha… - Laboratory …, 2000 - Elsevier
CONCLUSION The notion that inflammation is the net resultant of pro and contra
inflammatory pathways (Fauve, 1980) is well illustrated by the dual role of neutrophils which …

Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and …

KA Zarember, PJ Godowski - The journal of immunology, 2002 - journals.aai.org
Members of the Toll-like receptor (TLR) family mediate dorsoventral patterning and cellular
adhesion in insects as well as immune responses to microbial products in both insects and …

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family

DY Richard, F Boulay, JM Wang, C Dahlgren… - Pharmacological …, 2009 - Elsevier
Formyl peptide receptors (FPRs) are a small group of seven-transmembrane domain, G
protein-coupled receptors that are expressed mainly by mammalian phagocytic leukocytes …

[PDF][PDF] The neutrophil as a cellular source of chemokines

S Gasperini, F Calzetti, F Bazzoni, MA Cassatella - Immunol Rev, 2000 - academia.edu
Neutrophils are known to play an important role in inflammatory responses by virtue of their
ability to perform a series of effector functions that collectively represent a major mechanism …