Single-cell genomics has now made it possible to create a comprehensive atlas of human
cells. At the same time, it has reopened definitions of a cell's identity and of the ways in …

Phenotypically identical cells can dramatically vary with respect to behavior during their
lifespan and this variation is reflected in their molecular composition such as the …

Motivation: Single-cell technologies have recently gained popularity in cellular differentiation
studies regarding their ability to resolve potential heterogeneities in cell populations …

DNA is an ultrahigh-density storage medium that could meet exponentially growing
worldwide demand for archival data storage if DNA synthesis costs declined sufficiently and …

The existence of cellular heterogeneity and its central relevance to biological phenomena
provides a strong rationale for a need for analytical methods that enable analysis at the …

Flow cytometry is an essential tool for dissecting the functional complexity of hematopoiesis.
We used single-cell “mass cytometry” to examine healthy human bone marrow, measuring …

Nanomedicine | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Semiconductor quantum dots (QDs) are brightly luminescent nanoparticles that have found
numerous applications in bioanalysis and bioimaging. In this review, we highlight recent …

The ability to analyze multiple single-cell parameters is critical for understanding cellular
heterogeneity. Despite recent advances in measurement technology, methods for analyzing …

Stem cells are defined by the ability to self-renew and to generate differentiated progeny,
qualities that are maintained by evolutionarily conserved pathways that can lead to cancer …