[HTML][HTML] Insufficient evidence for “autism-specific” genes

SM Myers, TD Challman, R Bernier, T Bourgeron… - The American Journal of …, 2020 - cell.com
Despite evidence that deleterious variants in the same genes are implicated across multiple
neurodevelopmental and neuropsychiatric disorders, there has been considerable interest …

Rethinking the fast-slow continuum of individual differences

M Del Giudice - Evolution and Human Behavior, 2020 - Elsevier
The idea that individual differences in behavior and physiology can be partly understood by
linking them to a fast-slow continuum of life history strategies has become popular in the …

The p factor: genetic analyses support a general dimension of psychopathology in childhood and adolescence

AG Allegrini, R Cheesman, K Rimfeld… - Journal of child …, 2020 - Wiley Online Library
Background Diverse behaviour problems in childhood correlate phenotypically, suggesting
a general dimension of psychopathology that has been called the p factor. The shared …

Genetic estimates of correlation and causality between blood-based biomarkers and psychiatric disorders

WR Reay, DJ Kiltschewskij, MP Geaghan, JR Atkins… - Science …, 2022 - science.org
There is a long-standing interest in exploring the relationship between blood-based
biomarkers and psychiatric disorders, despite their causal role being difficult to resolve in …

Research Review: How to interpret associations between polygenic scores, environmental risks, and phenotypes

JB **ault, AG Allegrini, T Odigie… - Journal of Child …, 2022 - Wiley Online Library
Background Genetic influences are ubiquitous as virtually all phenotypes and most
exposures typically classified as environmental have been found to be heritable. A …

Practitioner Review: Attention‐deficit hyperactivity disorder and autism spectrum disorder–the importance of depression

A Thapar, LA Livingston, O Eyre… - Journal of Child …, 2023 - Wiley Online Library
Young people with neurodevelopmental disorders, such as attention‐deficit hyperactivity
disorder (ADHD) and autism spectrum disorder (ASD), show high rates of mental health …

[HTML][HTML] Cannabinoids for people with ASD: a systematic review of published and ongoing studies

L Fusar-Poli, V Cavone, S Tinacci, I Concas, A Petralia… - Brain sciences, 2020 - mdpi.com
The etiopathogenesis of autism spectrum disorder (ASD) remains largely unclear. Among
other biological hypotheses, researchers have evidenced an imbalance in the …

Research Review: The strength of the genetic overlap between ADHD and other psychiatric symptoms–a systematic review and meta‐analysis

A Andersson, C Tuvblad, Q Chen… - Journal of Child …, 2020 - Wiley Online Library
Background Attention‐deficit/hyperactivity disorder (ADHD) frequently co‐occurs with other
psychiatric disorders. Twin studies have established that these co‐occurrences are in part …

Topologically associating domains define the impact of de novo promoter variants on autism spectrum disorder risk

T Nakamura, J Ueda, S Mizuno, K Honda, A Kazuno… - Cell Genomics, 2024 - cell.com
Whole-genome sequencing (WGS) studies of autism spectrum disorder (ASD) have
demonstrated the roles of rare promoter de novo variants (DNVs). However, most promoter …

Familial and genetic associations between autism spectrum disorder and other neurodevelopmental and psychiatric disorders

L Ghirardi, R Kuja‐Halkola, A Butwicka… - Journal of Child …, 2021 - Wiley Online Library
Background Familial and genetic associations between autism spectrum disorder (ASD) and
other neurodevelopmental and psychiatric disorders have been reported, sometimes with …