Exploring the structural importance of the C3═ C4 double bond in plant alkaloids harmine and harmaline on their binding interactions with hemoglobin

MD Burman, S Bag, S Ghosal, S Karmakar… - ACS …, 2023 - ACS Publications
Harmine and harmaline are two structurally similar heterocyclic β-carboline plant alkaloids
with various therapeutic properties, having a slight structural difference in the C3═ C4 …

Microplastics can alter structural configurations of human non-canonical G-quadruplex DNA

S Bag, S Ghosal, S Bhowmik - Environmental Toxicology and …, 2025 - Elsevier
Microplastics (MP) with a diameter of less than 150 μm can enter the lymph and bloodstream
systems, induce cellular toxicity and damage DNA. G-quadruplexes (GQs) are tetraplex DNA …

Investigating the preferential interaction between imatinib mesylate and VEGF G-quadruplex DNA as therapeutic strategies for cancer treatment: Biophysical and …

S Ghosal, S Bag, RK Chinnadurai, M Mukherjee… - Computers in Biology …, 2024 - Elsevier
G-Quadruplex DNA (GQ–DNA) is one of the most important non-canonical nucleic acid
structures. GQ–DNA forming sequences are present in different crucial genomic regions and …

Quercetin Exhibits Preferential Binding Interaction by Selectively Targeting HRAS1 I-Motif DNA-Forming Promoter Sequences

S Bag, S Ghosal, M Mukherjee, G Pramanik… - Langmuir, 2024 - ACS Publications
I-Motif (iM) DNA structures represent among the most significant noncanonical nucleic acid
configurations. iM-forming DNA sequences are found in an array of vital genomic locations …

Decoding the Potential of HRAS2 i‐Motif DNA Promoter to Become a Pinpoint Target by Phytomedicine Naringenin

S Bag, S Ghosal, S Bhowmik - ChemistrySelect, 2025 - Wiley Online Library
Cytosine‐rich i‐motif (iM) DNA tetraplexes can influence oncogenic transcription and
develo** phytomedicines for iMs is a viable approach for cancer and other disease …

[HTML][HTML] Exploring i-Motif DNA binding with benzothiazolino Coumarins: Synthesis, Screening, and spectroscopic insights

S Bag, K Chand, MD Burman, S Vertueux, E Chorell… - Bioorganic …, 2025 - Elsevier
I-motif (iM) DNA structures are dynamic cytosine-rich secondary structures that are
increasingly recognized for their roles in transcriptional regulation, genomic stability, and for …