[HTML][HTML] Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria

Y Liu, Z Tong, J Shi, R Li, M Upton, Z Wang - Theranostics, 2021 - ncbi.nlm.nih.gov
Antimicrobial resistance has been a global health challenge that threatens our ability to
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …

Two-component sensing and regulation: how do histidine kinases talk with response regulators at the molecular level?

A Buschiazzo, F Trajtenberg - Annual review of microbiology, 2019 - annualreviews.org
Perceiving environmental and internal information and reacting in adaptive ways are
essential attributes of living organisms. Two-component systems are relevant protein …

[HTML][HTML] Cytokinins

JJ Kieber, GE Schaller - … Book/American Society of Plant Biologists, 2014 - ncbi.nlm.nih.gov
Cytokinins are N 6 substituted adenine derivatives that affect many aspects of plant growth
and development, including cell division, shoot initiation and growth, leaf senescence …

Function, structure and mechanism of bacterial photosensory LOV proteins

J Herrou, S Crosson - Nature reviews microbiology, 2011 - nature.com
LOV (light, oxygen or voltage) domains are protein photosensors that are conserved in
bacteria, archaea, plants and fungi, and detect blue light via a flavin cofactor. LOV domains …

Cache domains that are homologous to, but different from PAS domains comprise the largest superfamily of extracellular sensors in prokaryotes

AA Upadhyay, AD Fleetwood, O Adebali… - PLoS computational …, 2016 - journals.plos.org
Cellular receptors usually contain a designated sensory domain that recognizes the signal.
Per/Arnt/Sim (PAS) domains are ubiquitous sensors in thousands of species ranging from …

[HTML][HTML] Two-component systems and their co-option for eukaryotic signal transduction

GE Schaller, SH Shiu, JP Armitage - Current Biology, 2011 - cell.com
Two-component signaling pathways involve histidine kinases, response regulators, and
sometimes histidine-containing phosphotransfer proteins. Prevalent in prokaryotes, these …

Characterization of genes involved in cytokinin signaling and metabolism from rice

YC Tsai, NR Weir, K Hill, W Zhang, HJ Kim… - Plant …, 2012 - academic.oup.com
Two-component signaling elements play important roles in plants, including a central role in
cytokinin signaling. We characterized two-component elements from the monocot rice …

Origin and functional diversification of PAS domain, a ubiquitous intracellular sensor

J **ng, VM Gumerov, IB Zhulin - Science Advances, 2023 - science.org
Signal perception is a key function in regulating biological activities and adapting to
changing environments. Per-Arnt-Sim (PAS) domains are ubiquitous sensors found in …

The fight for invincibility: environmental stress response mechanisms and Aeromonas hydrophila

F Awan, Y Dong, N Wang, J Liu, K Ma, Y Liu - Microbial pathogenesis, 2018 - Elsevier
Aeromonas hydrophila is a freshwater-dwelling zoonotic bacterium that has economic
importance in aquaculture. In the past decade, Aeromonas hydrophila has become …

Diversity of bacterial chemosensory systems

VM Gumerov, EP Andrianova, IB Zhulin - Current opinion in microbiology, 2021 - Elsevier
Chemosensory system is the most complex, specialized mode of signal transduction in
bacteria and archaea. It is composed of several core and auxiliary protein components that …