Blood groups in infection and host susceptibility
L Cooling - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Blood group antigens represent polymorphic traits inherited among individuals and
populations. At present, there are 34 recognized human blood groups and hundreds of …
populations. At present, there are 34 recognized human blood groups and hundreds of …
Benign ethnic neutropenia
Benign ethnic neutropenia (BEN) is one of the most common causes of chronic neutropenia
seen in individuals of African, Middle Eastern and West Indian descent, affecting many …
seen in individuals of African, Middle Eastern and West Indian descent, affecting many …
Diversity and inclusion in genomic research: why the uneven progress?
AR Bentley, S Callier, CN Rotimi - Journal of community genetics, 2017 - Springer
Conducting genomic research in diverse populations has led to numerous advances in our
understanding of human history, biology, and health disparities, in addition to discoveries of …
understanding of human history, biology, and health disparities, in addition to discoveries of …
HIV and haematopoiesis
Human immunodeficiency virus (HIV) infection not only leads to a compromised immune
system, but also disrupts normal haematopoiesis, resulting in the frequent manifestation of …
system, but also disrupts normal haematopoiesis, resulting in the frequent manifestation of …
Innate immune activation enhances HIV acquisition in women, diminishing the effectiveness of tenofovir microbicide gel
The antiretroviral agent, tenofovir, formulated as a vaginal microbicide gel, reduces human
immunodeficiency virus (HIV) acquisition by 39% in women. This study assessed the role of …
immunodeficiency virus (HIV) acquisition by 39% in women. This study assessed the role of …
[HTML][HTML] Neutrophil extracellular traps prevent HIV infection in the female genital tract
FD Barr, C Ochsenbauer, CR Wira… - Mucosal …, 2018 - Elsevier
Women acquire human immunodeficiency virus (HIV) mainly through sexual intercourse.
However, low transmission rates per sexual act indicate that local immune mechanisms …
However, low transmission rates per sexual act indicate that local immune mechanisms …
Imputation of exome sequence variants into population-based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing …
Researchers have successfully applied exome sequencing to discover causal variants in
selected individuals with familial, highly penetrant disorders. We demonstrate the utility of …
selected individuals with familial, highly penetrant disorders. We demonstrate the utility of …
Haematological manifestations of human immune deficiency virus infection
P Vishnu, DM Aboulafia - British journal of haematology, 2015 - Wiley Online Library
Early in the human immunodeficiency virus (HIV) epidemic, infected patients presented to
medical attention with striking abnormalities in each of the major blood cell lineages. The …
medical attention with striking abnormalities in each of the major blood cell lineages. The …
LDtrait: an online tool for identifying published phenotype associations in linkage disequilibrium
Genome-wide association studies (GWAS) have identified thousands of germline
susceptibility loci associated with risk for cancer as well as a wide range of other traits and …
susceptibility loci associated with risk for cancer as well as a wide range of other traits and …
Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease
Genomic research is one of the tools for elucidating the pathogenesis of diseases of global
health relevance and paving the research dimension to clinical and public health translation …
health relevance and paving the research dimension to clinical and public health translation …