Sustaining the vital functions of cells outside the organism requires strictly defined
parameters. In order to ensure their optimal growth and development, it is necessary to …

Nanotechnology refers to the control, manipulation, study and manufacture of structures and
devices at the nanometer size range. The small size, customized surface, improved solubility …

The effectiveness of stem cell therapies has been hampered by cell death and limited
control over fate. These problems can be partially circumvented by using macroporous …

This review compiles information regarding the use of alginate, and in particular alginate
hydrogels, in culturing cells in 3D. Knowledge of alginate chemical structure and …

Alginate is a biomaterial that has found numerous applications in biomedical science and
engineering due to its favorable properties, including biocompatibility and ease of gelation …

Stem cells sense and respond to the mechanical properties of the extracellular matrix.
However, both the extent to which extracellular-matrix mechanics affect stem-cell fate in …

Alginate is a natural polysaccharide that is easily chemically modified or compounded with
other components for various types of functionalities. The alginate derivatives are appealing …

The ultimate goal in the design of biomimetic materials for use in tissue engineering as
permanent or resorbable tissue implants is to generate biocompatible scaffolds with …

A leading strategy in tissue engineering is the design of biomimetic scaffolds that stimulate
the body's repair mechanisms through the recruitment of endogenous stem cells to sites of …

Peptides, short protein fragments, can emulate the functions of their full-length native
counterparts. Peptides are considered potent recombinant protein alternatives due to their …