Interactions of intestinal bacteria with components of the intestinal mucus

JF Sicard, G Le Bihan, P Vogeleer… - Frontiers in cellular …, 2017 - frontiersin.org
The human gut is colonized by a variety of large amounts of microbes that are collectively
called intestinal microbiota. Most of these microbial residents will grow within the mucus …

Tripartite relationship between gut microbiota, intestinal mucus and dietary fibers: towards preventive strategies against enteric infections

T Sauvaitre, L Etienne-Mesmin… - FEMS Microbiology …, 2021 - academic.oup.com
The human gut is inhabited by a large variety of microorganims involved in many
physiological processes and collectively referred as to gut microbiota. Disrupted microbiome …

[HTML][HTML] Enterohemorrhagic Escherichia coli reduces mucus and intermicrovillar bridges in human stem cell-derived colonoids

J In, J Foulke-Abel, NC Zachos, AM Hansen… - Cellular and molecular …, 2016 - Elsevier
Background & Aims Enterohemorrhagic Escherichia coli (EHEC) causes over 70,000
episodes of foodborne diarrhea annually in the United States. The early sequence of events …

Mucin-Degrading Microbes Release Monosaccharides That Chemoattract Clostridioides difficile and Facilitate Colonization of the Human Intestinal Mucus Layer

MA Engevik, AC Engevik, KA Engevik… - ACS infectious …, 2020 - ACS Publications
It is widely accepted that the pathogen Clostridioides difficile exploits an intestinal
environment with an altered microbiota, but the details of these microbe–microbe …

Colonization resistance and microbial ecophysiology: using gnotobiotic mouse models and single-cell technology to explore the intestinal jungle

B Stecher, D Berry, A Loy - FEMS microbiology reviews, 2013 - academic.oup.com
The highly diverse intestinal microbiota forms a structured community engaged in constant
communication with itself and its host and is characterized by extensive ecological …

Enterohemorrhagic Escherichia coli senses low biotin status in the large intestine for colonization and infection

B Yang, L Feng, F Wang, L Wang - Nature communications, 2015 - nature.com
Enterohemorrhagic Escherichia coli (EHEC) is an important foodborne pathogen that infects
humans by colonizing the large intestine. Here we identify a virulence-regulating pathway in …

An Overview of the Elusive Passenger in the Gastrointestinal Tract of Cattle: The Shiga Toxin Producing Escherichia coli

P Sapountzis, A Segura, M Desvaux, E Forano - Microorganisms, 2020 - mdpi.com
For approximately 10,000 years, cattle have been our major source of meat and dairy.
However, cattle are also a major reservoir for dangerous foodborne pathogens that belong …

Host-Derived Sialic Acids Are an Important Nutrient Source Required for Optimal Bacterial Fitness In Vivo

ND McDonald, JB Lubin, N Chowdhury, EF Boyd - MBio, 2016 - Am Soc Microbiol
ABSTRACT A major challenge facing bacterial intestinal pathogens is competition for
nutrient sources with the host microbiota. Vibrio cholerae is an intestinal pathogen that …

Mucus-pathogen interactions in the gastrointestinal tract of farmed animals

MP Quintana-Hayashi, M Padra, JT Padra… - Microorganisms, 2018 - mdpi.com
Gastrointestinal infections cause significant challenges and economic losses in animal
husbandry. As pathogens becoming resistant to antibiotics are a growing concern …

Host sialic acids: a delicacy for the pathogen with discerning taste

BL Haines-Menges, WB Whitaker… - Metabolism and …, 2015 - Wiley Online Library
Sialic acids (neuraminic acids) are a diverse family of nine carbon (nonulosonic) α‐keto
acidic carbohydrates. The canonical sialic acid, 2‐keto‐3‐deoxy‐5‐acetamido‐D‐glycero‐D …