The role of myeloperoxidase in biomolecule modification, chronic inflammation, and disease

MJ Davies, CL Hawkins - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: The release of myeloperoxidase (MPO) by activated leukocytes is critical in
innate immune responses. MPO produces hypochlorous acid (HOCl) and other strong …

Free radicals: properties, sources, targets, and their implication in various diseases

A Phaniendra, DB Jestadi, L Periyasamy - Indian journal of clinical …, 2015 - Springer
Free radicals and other oxidants have gained importance in the field of biology due to their
central role in various physiological conditions as well as their implication in a diverse range …

Chemical and molecular mechanisms of antioxidants: experimental approaches and model systems

JM Lü, PH Lin, Q Yao, C Chen - Journal of cellular and …, 2010 - Wiley Online Library
Introduction• Free radical scavenging‐Scavenging superoxide and other ROS‐Scavenging
hydroxyl radical and other ROS‐Stable radical scavenging• Metal ion (Fe2+, Fe3+, Cu2+ …

The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer

E Middleton Jr, C Kandaswami… - Pharmacological reviews, 2000 - Elsevier
Flavonoids are nearly ubiquitous in plants and are recognized as the pigments responsible
for the colors of leaves, especially in autumn. They are rich in seeds, citrus fruits, olive oil …

The impact of plant flavonoids on mammalian biology: implications for immunity, inflammation and cancer

M Elliott, K Chithan - The flavonoids advances in research …, 2017 - api.taylorfrancis.com
15.4 Effects of flavonoids on smooth muscle 15.5 Antitoxic and hepatoprotective effects of
Oavonoids 15.6 Effects of flavonoids on other cells 15.7 Antiviral effects of flavonoids 15.8 …

Reconciling the chemistry and biology of reactive oxygen species

CC Winterbourn - Nature chemical biology, 2008 - nature.com
There is a vast literature on the generation and effects of reactive oxygen species in
biological systems, both in relation to damage they cause and their involvement in cell …

Surviving reactive chlorine stress: responses of gram-negative bacteria to hypochlorous acid

WS da Cruz Nizer, V Inkovskiy, J Overhage - Microorganisms, 2020 - mdpi.com
Sodium hypochlorite (NaOCl) and its active ingredient, hypochlorous acid (HOCl), are the
most commonly used chlorine-based disinfectants. HOCl is a fast-acting and potent …

Role of oxidative modifications in atherosclerosis

R Stocker, JF Keaney Jr - Physiological reviews, 2004 - journals.physiology.org
This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

[HTML][HTML] Sulfenic acid chemistry, detection and cellular lifetime

V Gupta, KS Carroll - Biochimica et Biophysica Acta (BBA)-General …, 2014 - Elsevier
Background Reactive oxygen species-mediated cysteine sulfenic acid modification has
emerged as an important regulatory mechanism in cell signaling. The stability of sulfenic …

The antioxidant activity of coumarins and flavonoids

G Borges Bubols, D da Rocha Vianna… - Mini reviews in …, 2013 - ingentaconnect.com
Coumarins and flavonoids are heterocyclic molecules that have been associated with
beneficial effects on human health, such as reducing the risk of cancer, diabetes …