Oncogenes and tumor suppressor genes: functions and roles in cancers

TC Dakal, B Dhabhai, A Pant, K Moar… - MedComm, 2024 - Wiley Online Library
Cancer, being the most formidable ailment, has had a profound impact on the human health.
The disease is primarily associated with genetic mutations that impact oncogenes and tumor …

Somatic evolution of cancer genes in sex chromosomes

A Marco, AC Akachukwu, JS Ratcliff - bioRxiv, 2024 - biorxiv.org
Genes on sex chromosomes have higher evolutionary rates than those on autosomes.
However, this does not necessarily apply to somatic evolution in cancer. Many dominant …

[PDF][PDF] Somatic evolution of cancer genes in sex chromosomes

AC Akachukwu, JS Ratcliff, A Marco - bioRxiv, 2024 - biorxiv.org
Genes on sex chromosomes have higher evolutionary rates than those on autosomes.
However, this does not necessarily apply to somatic evolution in cancer. Many dominant …