[HTML][HTML] Resistance of Candida to azoles and echinocandins worldwide

KE Pristov, MA Ghannoum - Clinical Microbiology and Infection, 2019 - Elsevier
Background Recently there has been an increase in Candida infections worldwide. A
handful of species in the genus Candida are opportunistic pathogens and have been known …

The global problem of antifungal resistance: prevalence, mechanisms, and management

DS Perlin, R Rautemaa-Richardson… - The Lancet infectious …, 2017 - thelancet.com
All serious fungal infections need appropriate antifungal therapy for successful patient
outcome. Only a few classes of antifungal drugs are available, so the emergence of …

Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment

MC Arendrup, TF Patterson - The Journal of infectious diseases, 2017 - academic.oup.com
Invasive Candida infections remain an important cause of morbidity and mortality, especially
in hospitalized and immunocompromised or critically ill patients. A limited number of …

Antifungal resistance: current trends and future strategies to combat

NP Wiederhold - Infection and drug resistance, 2017 - Taylor & Francis
Antifungal resistance represents a major clinical challenge to clinicians responsible for
treating invasive fungal infections due to the limited arsenal of systemically available …

[HTML][HTML] The quiet and underappreciated rise of drug-resistant invasive fungal pathogens

A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020 - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …

Mechanisms of echinocandin antifungal drug resistance

DS Perlin - Annals of the new York Academy of Sciences, 2015 - Wiley Online Library
Fungal infections due to Candida and Aspergillus species cause extensive morbidity and
mortality, especially among immunosuppressed patients, and antifungal therapy is critical to …

[HTML][HTML] Current antifungal drugs and immunotherapeutic approaches as promising strategies to treatment of fungal diseases

S Nami, A Aghebati-Maleki, H Morovati… - Biomedicine & …, 2019 - Elsevier
Invasive candidiasis (IC) can affect individuals with various underlying diseases hospitalized
in different parts of hospitals. In recent decades, IC has caused 27–55% mortality in general …

Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical …

TR Rogers, PE Verweij, M Castanheira… - Journal of …, 2022 - academic.oup.com
The increasing incidence and changing epidemiology of invasive fungal infections continue
to present many challenges to their effective management. The repertoire of antifungal drugs …

Resistance to antifungal drugs

R Ben-Ami, DP Kontoyiannis - Infectious Disease Clinics, 2021 - id.theclinics.com
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Emerging multidrug-resistant Candida species

AL Colombo, JN de Almeida Júnior… - Current Opinion in …, 2017 - journals.lww.com
We checked all papers published along the last 10 years describing epidemiological,
diagnostic, and clinical aspects of infections by MDR Candida spp., with emphasis on C …