A bibliometric review of drug repurposing
Highlights•A bibliometric review of drug repurposing provides novel insights into the
practice.•Some drugs have been tried in hundreds of diseases.•Even an old drug like …
practice.•Some drugs have been tried in hundreds of diseases.•Even an old drug like …
Metronomic chemotherapy and drug repurposing: A paradigm shift in oncology
Cancer represents a significant global health and economic burden due to its high mortality
rates. While effective in some instances, traditional chemotherapy often falls short of entirely …
rates. While effective in some instances, traditional chemotherapy often falls short of entirely …
Targeting the peripheral neural-tumour microenvironment for cancer therapy
As the field of cancer neuroscience expands, the strategic targeting of interactions between
neurons, cancer cells and other elements in the tumour microenvironment represents a …
neurons, cancer cells and other elements in the tumour microenvironment represents a …
[HTML][HTML] ReDO_DB: the repurposing drugs in oncology database
P Pantziarka, C Verbaanderd, V Sukhatme… - …, 2018 - ncbi.nlm.nih.gov
Repurposing is a drug development strategy that seeks to use existing medications for new
indications. In oncology, there is an increased level of activity looking at the use of non …
indications. In oncology, there is an increased level of activity looking at the use of non …
Biobehavioral pathways and cancer progression: insights for improving well-being and cancer outcomes
The relationship between psychosocial factors and cancer has intrigued people for
centuries. In the last several decades there has been an expansion of mechanistic research …
centuries. In the last several decades there has been an expansion of mechanistic research …
PEGylated silk nanoparticles for anticancer drug delivery
T Wongpinyochit, P Uhlmann, AJ Urquhart… - …, 2015 - ACS Publications
Silk has a robust clinical track record and is emerging as a promising biopolymer for drug
delivery, including its use as nanomedicine. However, silk-based nanomedicines still …
delivery, including its use as nanomedicine. However, silk-based nanomedicines still …
Vitamin D and regulation of vascular cell function
Vitamin D deficiency is linked to pathogenesis of many diseases including cardiovascular,
cancer, and various eye diseases. In recent years, important roles for vitamin D in regulation …
cancer, and various eye diseases. In recent years, important roles for vitamin D in regulation …
Metformin and propranolol combination prevents cancer progression and metastasis in different breast cancer models
M Rico, M Baglioni, M Bondarenko, NC Laluce… - …, 2016 - pmc.ncbi.nlm.nih.gov
Discovery of new drugs for cancer treatment is an expensive and time-consuming process
and the percentage of drugs reaching the clinic remains quite low. Drug repositioning refers …
and the percentage of drugs reaching the clinic remains quite low. Drug repositioning refers …
The potential to treat lung cancer via inhalation of repurposed drugs
Lung cancer is a highly invasive and prevalent disease with ineffective first-line treatment
and remains the leading cause of cancer death in men and women. Despite the …
and remains the leading cause of cancer death in men and women. Despite the …
Repurposing existing therapeutics, its importance in oncology drug development: Kinases as a potential target
Repurposing the large arsenal of existing non‐cancer drugs is an attractive proposition to
expand the clinical pipelines for cancer therapeutics. The earlier successes in repurposing …
expand the clinical pipelines for cancer therapeutics. The earlier successes in repurposing …