Biomarker-based staging of Alzheimer disease: rationale and clinical applications
Disease staging, whereby the spatial extent and load of brain pathology are used to
estimate the severity of Alzheimer disease (AD), is pivotal to the gold-standard …
estimate the severity of Alzheimer disease (AD), is pivotal to the gold-standard …
Apathy Associated with Alzheimer's Disease
D Wu, B Zhang, Y Chang… - Current Alzheimer …, 2024 - benthamdirect.com
Introduction/Objective Apathy is a multidimensional and complex disease that is the primary
neuropsychiatric symptom among those diagnosed with Alzheimer's disease (AD). Yet …
neuropsychiatric symptom among those diagnosed with Alzheimer's disease (AD). Yet …
Structural white matter properties and cognitive resilience to tau pathology
INTRODUCTION We assessed whether macro‐and/or micro‐structural white matter
properties are associated with cognitive resilience to Alzheimer's disease pathology years …
properties are associated with cognitive resilience to Alzheimer's disease pathology years …
Decoding meditation mechanisms underlying brain preservation and psycho-affective health in older expert meditators and older meditation-naive participants
S Haudry, AL Turpin, B Landeau, F Mézenge… - Scientific Reports, 2024 - nature.com
Meditation is a mental training approach that can improve mental health and well-being in
aging. Yet the underlying mechanisms remain unknown. The Medit-Ageing model stipulates …
aging. Yet the underlying mechanisms remain unknown. The Medit-Ageing model stipulates …
Loneliness and biomarkers of Alzheimer's disease, axonal damage, and astrogliosis: A coordinated analysis of two longitudinal cohorts
Objectives Loneliness is associated with an elevated risk of dementia. There is mixed
evidence from imaging studies on whether loneliness is associated with neuropathology in …
evidence from imaging studies on whether loneliness is associated with neuropathology in …
Trends in modifiable risk factors for dementia among midlife adults in the United States: The National Health and nutrition examination survey 1999–2018
Objective Dementia has a large public health burden, and modifiable risk factors, particularly
in midlife, may provide an opportunity for early prevention. We aimed to examine trends in …
in midlife, may provide an opportunity for early prevention. We aimed to examine trends in …
The speed limits for tau pathology progression in Alzheimer's disease
Objective To examine interactive effects of modifiable factors, genetic determinants and load-
dependent pathology effects on tau pathology progression. Methods Data of 162 amyloid …
dependent pathology effects on tau pathology progression. Methods Data of 162 amyloid …
Mental health and psychological processes associated with cognitive aging and dementia
D Bartrés-Faz, NL Marchant - Current Opinion in Neurology - journals.lww.com
The review emphasizes the need for greater focus on optimizing psychological well being,
particularly in at-risk populations, and suggests that interventions should be tailored to …
particularly in at-risk populations, and suggests that interventions should be tailored to …
[ספר][B] Interindividual differences in the brain during aging and Alzheimer's disease
F St-Onge - 2023 - search.proquest.com
Traditional brain imaging research designs typically include either a contrast of brain
features between two groups of interest, or an average of brain features within a single …
features between two groups of interest, or an average of brain features within a single …