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Advanced cell therapies for articular cartilage regeneration
Advanced cell-based therapies are promising approaches for stimulating full regeneration of
cartilage lesions. In addition to a few commercially available medicinal products, several …
cartilage lesions. In addition to a few commercially available medicinal products, several …
Tissue‐engineered cartilage: The crossroads of biomaterials, cells and stimulating factors
Damage to cartilage represents one of the most challenging tasks of musculoskeletal
therapeutics due to its limited propensity for healing and regenerative capabilities. Lack of …
therapeutics due to its limited propensity for healing and regenerative capabilities. Lack of …
Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds
PS Couto, MC Rotondi, A Bersenev, CJ Hewitt… - Biotechnology …, 2020 - Elsevier
Human mesenchymal stem/stromal cells (hMSCs) present a key therapeutic cellular
intervention for use in cell and gene therapy (CGT) applications due to their …
intervention for use in cell and gene therapy (CGT) applications due to their …
Scalable microcarrier-based manufacturing of mesenchymal stem/stromal cells
AM de Soure, A Fernandes-Platzgummer… - Journal of …, 2016 - Elsevier
Due to their unique features, mesenchymal stem/stromal cells (MSC) have been exploited in
clinical settings as therapeutic candidates for the treatment of a variety of diseases …
clinical settings as therapeutic candidates for the treatment of a variety of diseases …
Advanced therapy medicinal products: a guide for bone marrow-derived MSC application in bone and cartilage tissue engineering
D Confalonieri, A Schwab, H Walles… - Tissue Engineering Part …, 2018 - liebertpub.com
Millions of people worldwide suffer from trauma-or age-related orthopedic diseases such as
osteoarthritis, osteoporosis, or cancer. Tissue Engineering (TE) and Regenerative Medicine …
osteoarthritis, osteoporosis, or cancer. Tissue Engineering (TE) and Regenerative Medicine …
Stirred tank bioreactor culture combined with serum‐/xenogeneic‐free culture medium enables an efficient expansion of umbilical cord‐derived mesenchymal stem …
A Mizukami, A Fernandes‐Platzgummer… - Biotechnology …, 2016 - Wiley Online Library
Mesenchymal stem/stromal cells (MSC) are being widely explored as promising candidates
for cell‐based therapies. Among the different human MSC origins exploited, umbilical cord …
for cell‐based therapies. Among the different human MSC origins exploited, umbilical cord …
Compositional and structural analysis of glycosaminoglycans in cell-derived extracellular matrices
The extracellular matrix (ECM) is a highly dynamic and complex meshwork of proteins and
glycosaminoglycans (GAGs) with a crucial role in tissue homeostasis and organization not …
glycosaminoglycans (GAGs) with a crucial role in tissue homeostasis and organization not …
Combination of polyetherketoneketone scaffold and human mesenchymal stem cells from temporomandibular joint synovial fluid enhances bone regeneration
Therapies using human mesenchymal stem cells (MSCs) combined with three-dimensional
(3D) printed scaffolds are a promising strategy for bone grafting. But the harvest of MSCs still …
(3D) printed scaffolds are a promising strategy for bone grafting. But the harvest of MSCs still …
Integrated culture platform based on a human platelet lysate supplement for the isolation and scalable manufacturing of umbilical cord matrix‐derived mesenchymal …
AM de Soure… - Journal of Tissue …, 2017 - Wiley Online Library
Umbilical cord matrix (UCM)‐derived mesenchymal stem/stromal cells (MSCs) are
promising therapeutic candidates for regenerative medicine settings. UCM MSCs have …
promising therapeutic candidates for regenerative medicine settings. UCM MSCs have …
[HTML][HTML] The Myofibroblast Fate of Therapeutic Mesenchymal Stromal Cells: Regeneration, Repair, or Despair?
Mesenchymal stromal cells (MSCs) can be isolated from various tissues of healthy or patient
donors to be retransplanted in cell therapies. Because the number of MSCs obtained from …
donors to be retransplanted in cell therapies. Because the number of MSCs obtained from …