DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …

Air pollution associated epigenetic modifications: Transgenerational inheritance and underlying molecular mechanisms

A Shukla, N Bunkar, R Kumar, A Bhargava… - Science of the total …, 2019 - Elsevier
Air pollution is one of the leading causes of deaths in Southeast Asian countries including
India. Exposure to air pollutants affects vital cellular mechanisms and is intimately linked …

The nasal methylome as a biomarker of asthma and airway inflammation in children

A Cardenas, JE Sordillo, SL Rifas-Shiman… - Nature …, 2019 - nature.com
The nasal cellular epigenome may serve as biomarker of airway disease and environmental
response. Here we collect nasal swabs from the anterior nares of 547 children (mean-age …

Mediation by placental DNA methylation of the association of prenatal maternal smoking and birth weight

A Cardenas, SM Lutz, TM Everson… - American Journal of …, 2019 - academic.oup.com
Prenatal maternal smoking is a risk factor for lower birth weight. We performed epigenome-
wide association analyses of placental DNA methylation (DNAm) at 720,077 cytosine …

Environmental epigenetics and genome flexibility: Focus on 5-hydroxymethylcytosine

OA Efimova, AS Koltsova, MI Krapivin… - International Journal of …, 2020 - mdpi.com
Convincing evidence accumulated over the last decades demonstrates the crucial role of
epigenetic modifications for mammalian genome regulation and its flexibility. DNA …

[HTML][HTML] Prenatal methylmercury exposure and DNA methylation in seven-year-old children in the Seychelles Child Development Study

AC Ulloa, A Gliga, TM Love, D Pineda… - Environment …, 2021 - Elsevier
Abstract Background Methylmercury (MeHg) is present in fish and is a neurotoxicant at
sufficiently high levels. One potential mechanism of MeHg toxicity early in life is epigenetic …

Genetics, epigenetics, and transcriptomics of preterm birth

VG Jain, N Monangi, G Zhang… - American Journal of …, 2022 - Wiley Online Library
Preterm birth contributes significantly to neonatal mortality and morbidity. Despite its global
significance, there has only been limited progress in preventing preterm birth. Spontaneous …

Epigenetic age acceleration is associated with allergy and asthma in children in Project Viva

C Peng, A Cardenas, SL Rifas-Shiman… - Journal of Allergy and …, 2019 - Elsevier
Background Epigenetic clocks have been suggested to capture one feature of the
complexity between aging and the epigenome. However, little is known about the epigenetic …

Methylmercury and developmental neurotoxicity: A global concern

J Aaseth, DR Wallace, K Vejrup, J Alexander - Current Opinion in …, 2020 - Elsevier
Methylmercury (MeHg) is a globally relevant environmental neurotoxic pollutant. Recent
evidence from the Faroe Islands and Seychelles cohort studies suggest that maternal …

[HTML][HTML] Heavy Metals in Umbilical Cord Blood: Effects on Epigenetics and Child Development

S Dutta, DM Ruden - Cells, 2024 - mdpi.com
Heavy metals like arsenic, mercury, cadmium, and lead are harmful pollutants that can
change how our genes are regulated without altering the DNA sequence, specifically …