[HTML][HTML] Why do we study animal toxins?
Y Zhang - Zoological research, 2015 - ncbi.nlm.nih.gov
Venom (toxins) is an important trait evolved along the evolutionary tree of animals. Our
knowledges on venoms, such as their origins and loss, the biological relevance and the …
knowledges on venoms, such as their origins and loss, the biological relevance and the …
Venomics: a new paradigm for natural products-based drug discovery
The remarkable potency and pharmacological diversity of animal venoms has made them
an increasingly valuable source of lead molecules for drug and insecticide discovery …
an increasingly valuable source of lead molecules for drug and insecticide discovery …
Introducing BASE: the Biomes of Australian Soil Environments soil microbial diversity database
Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …
Molecular phylogeny and evolution of the cone snails (Gastropoda, Conoidea)
We present a large-scale molecular phylogeny that includes 320 of the 761 recognized valid
species of the cone snails (Conus), one of the most diverse groups of marine molluscs …
species of the cone snails (Conus), one of the most diverse groups of marine molluscs …
Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom
Cone snails produce highly complex venom comprising mostly small biologically active
peptides known as conotoxins or conopeptides. Early estimates that suggested 50–200 …
peptides known as conotoxins or conopeptides. Early estimates that suggested 50–200 …
Venomics as a drug discovery platform
P Escoubas, GF King - Expert review of proteomics, 2009 - Taylor & Francis
Modern drug discovery is increasingly in need of a novel paradigm to replace the classical
blockbuster-based economic model of large pharmaceutical companies. Loss of patent …
blockbuster-based economic model of large pharmaceutical companies. Loss of patent …
Venom composition and strategies in spiders: is everything possible?
L Kuhn-Nentwig, R Stöcklin, W Nentwig - Advances in insect physiology, 2011 - Elsevier
This review on all spider venom components known by the end of 2010 bases on 1618
records for venom compounds from 174 spider species (= 0.41% of all known species) …
records for venom compounds from 174 spider species (= 0.41% of all known species) …
Jellyfish venomics and venom gland transcriptomics analysis of Stomolophus meleagris to reveal the toxins associated with sting
R Li, H Yu, W Xue, Y Yue, S Liu, R ** parts of the world, with tens of
thousands of deaths and a multitude of lingering permanent medical conditions on a yearly …
thousands of deaths and a multitude of lingering permanent medical conditions on a yearly …
Cone snail venomics: from novel biology to novel therapeutics
Peptide neurotoxins from cone snails called conotoxins are renowned for their therapeutic
potential to treat pain and several neurodegenerative diseases. Inefficient assay-guided …
potential to treat pain and several neurodegenerative diseases. Inefficient assay-guided …