The Glasgow Outcome Scale—40 years of application and refinement

T McMillan, L Wilson, J Ponsford, H Levin… - Nature Reviews …, 2016 - nature.com
Abstract The Glasgow Outcome Scale (GOS) was first published in 1975 by Bryan Jennett
and Michael Bond. With over 4,000 citations to the original paper, it is the most highly cited …

Prognostication after cardiac arrest

C Sandroni, S D'Arrigo, JP Nolan - Critical care, 2018 - Springer
Hypoxic–ischaemic brain injury (HIBI) is the main cause of death in patients who are
comatose after resuscitation from cardiac arrest. A poor neurological outcome—defined as …

Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III …

DF Hanley, K Lane, N McBee, W Ziai, S Tuhrim… - The Lancet, 2017 - thelancet.com
Background Intraventricular haemorrhage is a subtype of intracerebral haemorrhage, with
50% mortality and serious disability for survivors. We aimed to test whether attempting to …

Longitudinal follow-up of patients with traumatic brain injury: outcome at two, five, and ten years post-injury

JL Ponsford, MG Downing, J Olver… - Journal of …, 2014 - liebertpub.com
The deleterious consequences of traumatic brain injury (TBI) impair capacity to return to
many avenues of pre-morbid life. However, there has been limited longitudinal research …

Diagnostic precision of PET imaging and functional MRI in disorders of consciousness: a clinical validation study

J Stender, O Gosseries, MA Bruno, V Charland-Verville… - The Lancet, 2014 - thelancet.com
Background Bedside clinical examinations can have high rates of misdiagnosis of
unresponsive wakefulness syndrome (vegetative state) or minimally conscious state. The …

Decompressive craniectomy in diffuse traumatic brain injury

DJ Cooper, JV Rosenfeld, L Murray… - … England Journal of …, 2011 - Mass Medical Soc
Background It is unclear whether decompressive craniectomy improves the functional
outcome in patients with severe traumatic brain injury and refractory raised intracranial …

Clinical trials in head injury

RK Narayan, ME Michel, B Ansell… - Journal of …, 2002 - liebertpub.com
Traumatic brain injury (TBI) remains a major public health problem globally. In the United
States the incidence of closed head injuries admitted to hospitals is conservatively estimated …

Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial

A Nichol, C French, L Little, S Haddad, J Presneill… - The Lancet, 2015 - thelancet.com
Background Erythropoietin might have neurocytoprotective effects. In this trial, we studied its
effect on neurological recovery, mortality, and venous thrombotic events in patients with …

[HTML][HTML] Saline or albumin for fluid resuscitation in patients with traumatic brain injury

SAFE Study Investigators - New England Journal of Medicine, 2007 - Mass Medical Soc
Background The Saline versus Albumin Fluid Evaluation study suggested that patients with
traumatic brain injury resuscitated with albumin had a higher mortality rate than those …

Disability in young people and adults one year after head injury: prospective cohort study

S Thornhill, GM Teasdale, GD Murray, J McEwen… - Bmj, 2000 - bmj.com
Objective: To determine the frequency of disability in young people and adults admitted to
hospital with a head injury and to estimate the annual incidence in the community. Design …