The heterogeneity of tissue macrophages, in health and in disease, has become
increasingly transparent over the last decade. But with the plethora of data comes a natural …

Single-cell and spatial transcriptomic technologies have revealed an underappreciated
heterogeneity of liver macrophages. This has led us to rethink the involvement of …

Anemia of inflammation (AI), also known as anemia of chronic disease (ACD), is regarded
as the most frequent anemia in hospitalized and chronically ill patients. It is prevalent in …

Macrophages, which are key cellular components of the liver, have emerged as essential
players in the maintenance of hepatic homeostasis and in injury and repair processes in …

Embryo-derived tissue-resident macrophages are the first representatives of the
haematopoietic lineage to emerge in metazoans. In mammals, resident macrophages …

Novel experimental approaches such as fate-map** and single-cell analysis have brought
fresh insight into monocyte development and function over the past decade and helped …

Macrophages represent a key cellular component of the liver, and are essential for
maintaining tissue homeostasis and ensuring rapid responses to hepatic injury. Our …

200 billion red blood cells (RBCs) are produced every day, requiring more than 2× 10 15
iron atoms every second to maintain adequate erythropoiesis. These numbers translate into …

Iron deficiency anaemia is a global health concern affecting children, women and the
elderly, whilst also being a common comorbidity in multiple medical conditions. The …

Abstract Haem oxygenase 1 (HO-1), an inducible enzyme responsible for the breakdown of
haem, is primarily considered an antioxidant, and has long been overlooked by …