Proton beam therapy for cancer in the era of precision medicine

M Hu, L Jiang, X Cui, J Zhang, J Yu - Journal of hematology & oncology, 2018 - Springer
Precision radiotherapy, which accurately delivers the dose on a tumor and confers little or no
irradiation to the surrounding normal tissue and organs, results in maximum tumor control …

Dual-and multi-energy CT for particle stop**-power estimation: current state, challenges and potential

M Yang, P Wohlfahrt, C Shen… - Physics in Medicine & …, 2023 - iopscience.iop.org
Range uncertainty has been a key factor preventing particle radiotherapy from reaching its
full physical potential. One of the main contributing sources is the uncertainty in estimating …

Experimental comparison of proton CT and dual energy x-ray CT for relative stop** power estimation in proton therapy

G Dedes, J Dickmann, K Niepel, P Wesp… - Physics in Medicine …, 2019 - iopscience.iop.org
Proton computed tomography (pCT) has been proposed as an alternative to x-ray computed
tomography (CT) for acquiring relative to water stop** power (RSP) maps used for proton …

Status and innovations in pre-treatment CT imaging for proton therapy

P Wohlfahrt, C Richter - The British journal of radiology, 2020 - academic.oup.com
Pre-treatment CT imaging is a topic of growing importance in particle therapy. Improvements
in the accuracy of stop**-power prediction are demanded to allow for a dose conformality …

[HTML][HTML] First-in-human validation of CT-based proton range prediction using prompt gamma imaging in prostate cancer treatments

J Berthold, C Khamfongkhruea, J Petzoldt… - International Journal of …, 2021 - Elsevier
Purpose Uncertainty in computed tomography (CT)-based range prediction substantially
impairs the accuracy of proton therapy. Direct determination of the stop**-power ratio …

X-ray computed tomography for effective atomic number and density evaluation: A review

MG Lima, EI Jussiani - Radiation Physics and Chemistry, 2024 - Elsevier
X-ray computed tomography (CT) is widely used in various fields, including medical,
industrial, and fundamental scientific applications. Its quick ability to provide three …

[HTML][HTML] Inter-centre variability of CT-based stop**-power prediction in particle therapy: survey-based evaluation

VT Taasti, C Bäumer, CV Dahlgren, AJ Deisher… - Physics and imaging in …, 2018 - Elsevier
Background and purpose Stop**-power ratios (SPRs) are used in particle therapy to
calculate particle range in patients. The heuristic CT-to-SPR conversion (Hounsfield Look …

Cone‐beam CT‐derived relative stop** power map generation via deep learning for proton radiotherapy

J Harms, Y Lei, T Wang, M McDonald… - Medical …, 2020 - Wiley Online Library
Purpose In intensity‐modulated proton therapy (IMPT), protons are used to deliver highly
conformal dose distributions, targeting tumors, and sparing organs‐at‐risk. However, due to …

Revisiting the single-energy CT calibration for proton therapy treatment planning: a critical look at the stoichiometric method

C Gomà, IP Almeida, F Verhaegen - Physics in Medicine & …, 2018 - iopscience.iop.org
Despite extensive research in dual-energy computed tomography (CT), single-energy CT
(SECT) is still the standard imaging modality in proton therapy treatment planning and, in …

Optimized I-values for use with the Bragg additivity rule and their impact on proton stop** power and range uncertainty

E Bär, P Andreo, A Lalonde, G Royle… - Physics in Medicine & …, 2018 - iopscience.iop.org
Novel imaging modalities can improve the estimation of patient elemental compositions for
particle treatment planning. The mean excitation energy (I-value) is a main contributor to the …