Cells have a constant turnover of proteins that recycle most amino acids over time. Net loss
is mainly due to amino acid oxidation. Homeostasis is achieved through exchange of …

Coronaviruses are a group of viruses causing disease in a wide range of animals, and
humans. Since 2002, the successive emergence of bat-borne severe acute respiratory …

The SLC (solute carrier)-type transporters (~ 400 in number) in mammalian cells consist of
52 distinct gene families, grouped solely based on the amino acid sequence (primary …

The bowhead whale (Balaena mysticetus) is estimated to live over 200 years and is possibly
the longest-living mammal. These animals should possess protective molecular adaptations …

Sodium-dependent neutral amino acid transporter B 0 AT1 (SLC6A19) and imino acid
(proline) transporter SIT1 (SLC6A20) are expressed at the luminal membrane of small …

Glutamine together with glucose is essential for body's homeostasis. It is the most abundant
amino acid and is involved in many biosynthetic, regulatory and energy production …

ACE2 is a type I membrane protein with extracellular carboxypeptidase activity displaying a
broad tissue distribution with highest expression levels at the brush border membrane …

The small intestine mediates the absorption of amino acids after ingestion of protein and
sustains the supply of amino acids to all tissues. The small intestine is an important …

Discovery of ACE2 (angiotensin-converting enzyme 2) revealed that the renin-angiotensin
system has 2 counterbalancing arms. ACE2 is a major player in the protective arm, highly …

Amino acid homeostasis is maintained by import, export, oxidation, and synthesis of
nonessential amino acids, and by the synthesis and breakdown of protein. These processes …