The sodium and potassium gradients across the plasma membrane are used by animal cells
for numerous processes, and the range of demands requires that the responsible ion pump …

The polarity of neurons, which is integral to their function, is a result of the segregated
distribution of molecules and organelles. The polarized distribution of cytoskeletal proteins …

Polarized epithelial cells play fundamental roles in the ontogeny and function of a variety of
tissues and organs in mammals. The morphogenesis of a sheet of polarized epithelial cells …

Epstein-Barr virus (EBV) initially enters the body through the oropharyngeal mucosa and
subsequently infects B lymphocytes through their CD21 (CR2) complement receptor …

To study the intracellular transport of newly synthesized sphingolipids in epithelial cells we
have used a fluorescent ceramide analog, N-6 [7-nitro-2, 1, 3-benzoxadiazol-4-yl] …

Glycosyl-phosphatidylinositol-(GPI) anchored proteins contain a large extracellular protein
domain that is linked to the membrane via a glycosylated form of phosphatidylinositol. We …

Preimplantation or pre-attachment development encompasses the" free"-living period of
mammalian embryogenesis, which directs development of the zygote through to the …

Kidney organ culture was used to study the conversion of embryonic mesenchymal cells into
a polarized, differentiated kidney epithelium. We examined the expression of laminin, a …

Summary Na+, K+-ATPase has distinctly different distributions in mesenchymal cells, where
it has an unrestricted distribution over the entire cell surface, compared with polarized …

Renal dysfunctions usually happen in viral infections and many viruses specially infect distal
renal tubules, however the pathogenesis remains unknown. Here, in order to explore the …