Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …

The brain is a highly energy-demanding organ and requires bioenergetic adaptability to
balance normal activity with pathophysiological fuelling of spontaneous recurrent seizures …

Since it was first generally accepted that the two amino acids glutamate and GABA act as
principal neurotransmitters, several landmark discoveries relating to this function have been …

Medium chain fatty acids (MCFAs) has unique transport system and is rapidly metabolized in
the body. It mainly occurs in coconut oil, palm kernel oil and milk products. Dietary …

The POLG gene encodes the mitochondrial DNA polymerase that is responsible for
replication of the mitochondrial genome. Mutations in POLG can cause early childhood …

High-fat, low-carbohydrate diets, known as ketogenic diets, have been used as a non-
pharmacological treatment for refractory epilepsy. A key mechanism of this treatment is …

Evidence supporting that gut problems are linked to ASD symptoms has been accumulating
both in humans and animal models of ASD. Gut microbes and their metabolites may be …

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Abstract AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid)-subtype ionotropic
glutamate receptors mediate fast excitatory neurotransmission throughout the central …

Medium chain triglycerides (MCT) are esters of fatty acids with 6 to 12 carbon atom chains.
Naturally, they occur in various sources; their composition and bioactivity are source and …