Philosophers defined the eye as a window to the soul long before scientists addressed this
cliché to determine its scientific basis and clinical relevance. Anatomically and …

Pathological evaluation is the gold standard for identifying processes related to multiple
sclerosis that explain disease manifestations, and for guiding the development of new …

Objective The aim of this work was to determine whether atrophy of specific retinal layers
and brain substructures are associated over time, in order to further validate the utility of …

Optical coherence tomography (OCT) is a new method that could aid analysis of
neurodegeneration in multiple sclerosis (MS) by capturing thinning of the retinal nerve fibre …

Objective To evaluate changes over 3 years in the thickness of inner retinal layers including
the peripapillary retinal nerve fiber layer (pRNFL), and combined macular ganglion cell and …

Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts
of information about the structure, function and molecular composition of retinal tissue in …

To summarize recent findings regarding the utility of optical coherence tomography in
multiple sclerosis. We searched PubMed for relevant articles using the keywords 'optical …

Macular oedema typically results from blood–retinal barrier disruption. It has recently been
reported that patients with multiple sclerosis treated with FTY-720 (fingolimod) may exhibit …

Visual impairment is a key manifestation of multiple sclerosis. Acute optic neuritis is a
common, often presenting manifestation, but visual deficits and structural loss of retinal …

Optical coherence tomography studies in multiple sclerosis have primarily focused on
evaluation of the retinal nerve fibre layer. The aetiology of retinal changes in multiple …