The anti-tumor activity of the immune system is increasingly recognized as critical for the
mounting of a prolonged and effective response to cancer growth and invasion, and for …

Drug development in oncology commonly exploits the tools of molecular biology to gain
therapeutic benefit through reprograming of cellular responses. In immuno‐oncology (IO) …

Determining the mathematical dynamics and associated parameter values that should be
used to accurately reflect tumor growth continues to be of interest to mathematical modelers …

Tumor-immune interactions are often framed as predator-prey. This imperfect analogy
describes how immune cells (the predators) hunt and kill immunogenic tumor cells (the …

In the present paper, we address by means of mathematical modeling the following main
question: How can oncolytic virus infection of some normal cells in the vicinity of tumor cells …

Cancer therapies that harness the actions of the immune response, such as targeted
monoclonal antibody treatments and therapeutic vaccines, are relatively new and promising …

Immunotherapy, by enhancing the endogenous anti-tumor immune responses, is showing
promising results for the treatment of numerous cancers refractory to conventional therapies …

Background Chemotherapy is usually known as the main modality for cancer treatment.
Nevertheless, most of chronic cancers could not be treated with chemotherapy alone …

Simple Summary Osteosarcoma is the most common primary bone tumor and has a poor
prognosis. Therefore, it is important to understand the mechanism of the development of …

In this study, a mathematical model of triple negative breast cancer (TNBC) with checkpoint
inhibitor immunotherapy is proposed. The mathematical model includes interactions …