Hypothalamus‐pituitary‐thyroid axis

TM Ortiga‐Carvalho, MI Chiamolera… - Comprehensive …, 2011 - Wiley Online Library
The hypothalamus‐pituitary‐thyroid (HPT) axis determines the set point of thyroid hormone
(TH) production. Hypothalamic thyrotropin‐releasing hormone (TRH) stimulates the …

Thyroid hormone and seasonal rhythmicity

H Dardente, DG Hazlerigg, FJP Ebling - Frontiers in endocrinology, 2014 - frontiersin.org
Living organisms show seasonality in a wide array of functions such as reproduction,
fattening, hibernation, and migration. At temperate latitudes, changes in photoperiod …

Influence of photoperiod on hormones, behavior, and immune function

JC Walton, ZM Weil, RJ Nelson - Frontiers in neuroendocrinology, 2011 - Elsevier
Photoperiodism is the ability of plants and animals to measure environmental day length to
ascertain time of year. Central to the evolution of photoperiodism in animals is the adaptive …

Photoperiodic regulation of reproduction in vertebrates

Y Nakane, T Yoshimura - Annual review of animal biosciences, 2019 - annualreviews.org
Organisms use changes in photoperiod for seasonal reproduction to maximize the survival
of their offspring. Birds have sophisticated seasonal mechanisms and are therefore excellent …

Involvement of thyrotropin in photoperiodic signal transduction in mice

H Ono, Y Hoshino, S Yasuo, M Watanabe… - Proceedings of the …, 2008 - pnas.org
Local thyroid hormone catabolism within the mediobasal hypothalamus (MBH) by thyroid
hormone-activating (DIO2) and-inactivating (DIO3) enzymes regulates seasonal …

Hypothalamic thyroid hormone catabolism acts as a gatekeeper for the seasonal control of body weight and reproduction

P Barrett, FJP Ebling, S Schuhler, D Wilson… - …, 2007 - academic.oup.com
Seasonal adaptations in physiology exhibited by many animals involve an interface
between biological timing and specific neuroendocrine systems, but the molecular basis of …

Reversible DNA methylation regulates seasonal photoperiodic time measurement

TJ Stevenson, BJ Prendergast - Proceedings of the National Academy of …, 2013 - pnas.org
In seasonally breeding vertebrates, changes in day length induce categorically distinct
behavioral and reproductive phenotypes via thyroid hormone-dependent mechanisms …

Universality and diversity in the signal transduction pathway that regulates seasonal reproduction in vertebrates

Y Nakane, T Yoshimura - Frontiers in neuroscience, 2014 - frontiersin.org
Most vertebrates living outside the tropical zone show robust physiological responses in
response to seasonal changes in photoperiod, such as seasonal reproduction, molt, and …

A vitamin for the brain

KD Shearer, PN Stoney, PJ Morgan… - Trends in neurosciences, 2012 - cell.com
In the central nervous system (CNS) the function of retinoic acid, the active metabolite of
vitamin A, is best understood from its action in guiding embryonic development; as …

Thyroid hormone and seasonal regulation of reproduction

T Yoshimura - Frontiers in neuroendocrinology, 2013 - Elsevier
Organisms living outside the tropics use changes in photoperiod to adapt to seasonal
changes in the environment. Several models have contributed to an understanding of this …