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Obesity-related knee osteoarthritis—current concepts
R Shumnalieva, G Kotov, S Monov - Life, 2023 - mdpi.com
The knee is the joint most frequently involved in osteoarthritis and represents a significant
contributor to patient morbidity and impaired functional status. Major risk factors include …
contributor to patient morbidity and impaired functional status. Major risk factors include …
Obesity as a disease: a pressing need for alignment
A Grannell, C le Roux - International Journal of Obesity, 2024 - nature.com
Obesity as a chronic disease, while generally accepted in healthcare, remains a contentious
subject in the public. The pathway towards health equity from a treatment standpoint for …
subject in the public. The pathway towards health equity from a treatment standpoint for …
Association between lipid accumulation products and osteoarthritis among adults in the United States: A cross-sectional study, NHANES 2017-2020
J Huang, J Han, R Rozi, B Fu, Z Lu, J Liu, Y Ding - Preventive Medicine, 2024 - Elsevier
Objective Using cross-sectional data from the 2017–2020 National Health and Nutrition
Examination Survey (NHANES) for American, the aim of this research is to investigate the …
Examination Survey (NHANES) for American, the aim of this research is to investigate the …
Association between body roundness index and risk of osteoarthritis: a cross-sectional study
X Wang, Z Guo, M Wang, C **ang - Lipids in Health and Disease, 2024 - Springer
Background The link between body roundness index (BRI) and osteoarthritis (OA) has yet to
be validated. Our aim was to explore this connection between BRI and OA risk. Methods …
be validated. Our aim was to explore this connection between BRI and OA risk. Methods …
Enhancement of Intracellular Cholesterol Efflux in Chondrocytes Leading to Alleviation of Osteoarthritis Progression
G Lee, J Yang, SJ Kim, TT Tran, SY Lee… - Arthritis & …, 2025 - Wiley Online Library
Objective Osteoarthritis (OA) is the most common degenerative disease worldwide, with no
practical means of prevention and limited treatment options. Recently, our group unveiled a …
practical means of prevention and limited treatment options. Recently, our group unveiled a …
Pathogenic mechanisms and therapeutic approaches in obesity-related knee osteoarthritis
R Shumnalieva, G Kotov, P Ermencheva, S Monov - Biomedicines, 2023 - mdpi.com
The knee is the joint most frequently involved in osteoarthritis, a common joint disorder in the
adult population that is associated with significant chronic joint pain, reduced mobility and …
adult population that is associated with significant chronic joint pain, reduced mobility and …
Proteomic and lipidomic landscape of the infrapatellar fat pad and its clinical significance in knee osteoarthritis
B Tu, Z Zhu, P Lu, R Fang, C Peng, J Tong… - Biochimica et Biophysica …, 2024 - Elsevier
Osteoarthritis (OA) is a prevalent joint disease that can be exacerbated by lipid metabolism
disorders. The intra-articular fat pad (IFP) has emerged as an active participant in the …
disorders. The intra-articular fat pad (IFP) has emerged as an active participant in the …
Obesity and hyperlipidemia were associated with more severe synovitis and structural abnormalities as well as inferior functional outcomes in knee osteoarthritis: a …
K Hao, J Wang, Y Niu, F Wang - Journal of Orthopaedic Surgery and …, 2024 - Springer
Background Considering that the respective effects of obesity and hyperlipidemia on knee
osteoarthritis (OA) have not been fully investigated, the purpose of this study was to …
osteoarthritis (OA) have not been fully investigated, the purpose of this study was to …
The association between ADAMTS14/rs4747096 gene polymorphism and some risk factors and knee osteoarthritis
Knee osteoarthritis (KOA) is an important cause of disability in the world and it denotes a
public health defiance of the upcoming years. Aim To examine the connection between …
public health defiance of the upcoming years. Aim To examine the connection between …
The Function and Mechanism of Anti-Inflammatory Factor Metrnl Prevents the Progression of Inflammatory-Mediated Pathological Bone Osteolytic Diseases
N Liu, J Dong, L Li, D Zhou, F Liu - Journal of Inflammation …, 2024 - Taylor & Francis
Metrnl, recently identified as an adipokine, is a secreted protein notably expressed in white
adipose tissue, barrier tissues, and activated macrophages. This adipokine plays a pivotal …
adipose tissue, barrier tissues, and activated macrophages. This adipokine plays a pivotal …