EMT-related cell-matrix interactions are linked to states of cell unjamming in cancer spheroid invasion

A van der Net, Z Rahman, AD Bordoloi, I Muntz… - iScience, 2024 - cell.com
Epithelial-to-mesenchymal transitions (EMT) and unjamming transitions provide two distinct
pathways for cancer cells to become invasive, but it is still unclear to what extent these …

EMT-dependent cell-matrix interactions are linked to unjamming transitions in cancer spheroid invasion

A van der Net, Z Rahman, AD Bordoloi, I Muntz… - bioRxiv, 2024 - biorxiv.org
The plasticity of cancer cells allows them to switch between different migration modes,
promoting their invasion into the extracellular matrix (ECM) and hence increasing the risks of …

Chromatin network rearrangements in differentiation and cancer reveal connections between evolutionary processes and gene regulation

B Aliaga, F Raynal, K Sengupta, D Plewczynski… - bioRxiv, 2023 - biorxiv.org
The availability of unprecedented datasets detailing the organization of chromatin across
species, developmental stages, cell types and diseases invites an integrated analysis of …