Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma
Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in
foods such as coffee, wine, tea, and popular medicines such as propolis. This phenolic acid …
foods such as coffee, wine, tea, and popular medicines such as propolis. This phenolic acid …
[HTML][HTML] IL-6 pathway in the liver: from physiopathology to therapy
Summary Interleukin 6 (IL-6) is a pleiotropic four-helix-bundle cytokine that exerts multiple
functions in the body. In the liver, IL-6 is an important inducer of the acute phase response …
functions in the body. In the liver, IL-6 is an important inducer of the acute phase response …
The role of interleukin 6 during viral infections
L Velazquez-Salinas, A Verdugo-Rodriguez… - Frontiers in …, 2019 - frontiersin.org
Our recently published research on the characterization of vesicular stomatitis virus (VSV)
pathogenesis in swine, identified a systemic upregulation of interleukin 6 (IL-6) during the …
pathogenesis in swine, identified a systemic upregulation of interleukin 6 (IL-6) during the …
The role of IL-6 in host defence against infections: immunobiology and clinical implications
IL-6 is a pleiotropic cytokine with broad-ranging effects within the integrated immune
response. One of the roles of IL-6 is to support immunocompetence, defined as the ability of …
response. One of the roles of IL-6 is to support immunocompetence, defined as the ability of …
Circulating and intrahepatic antiviral B cells are defective in hepatitis B
AR Burton, LJ Pallett, LE McCoy… - The Journal of …, 2018 - Am Soc Clin Investig
B cells are increasingly recognized as playing an important role in the ongoing control of
hepatitis B virus (HBV). The development of antibodies against the viral surface antigen …
hepatitis B virus (HBV). The development of antibodies against the viral surface antigen …
NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma
Hepatic cirrhosis and hepatocellular carcinoma (HCC) are the most common causes of
death in patients with chronic liver disease. Chronic liver injury of virtually any etiology …
death in patients with chronic liver disease. Chronic liver injury of virtually any etiology …
Hepatitis B virus infection
MF Yuen, DS Chen, GM Dusheiko… - Nature reviews Disease …, 2018 - nature.com
Hepatitis B virus (HBV) is a hepatotropic virus that can establish a persistent and chronic
infection in humans through immune anergy. Currently, 3.5% of the global population is …
infection in humans through immune anergy. Currently, 3.5% of the global population is …
Living in the liver: hepatic infections
The liver has vital metabolic and clearance functions that involve the uptake of nutrients,
waste products and pathogens from the blood. In addition, its unique immunoregulatory …
waste products and pathogens from the blood. In addition, its unique immunoregulatory …
Republished: Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection
A Bertoletti, C Ferrari - Postgraduate Medical Journal, 2013 - academic.oup.com
Abstract Knowledge of the immunological events necessary to control hepatitis B virus
(HBV) infection has accelerated in recent years, but their translation towards therapeutic …
(HBV) infection has accelerated in recent years, but their translation towards therapeutic …
3D microfluidic liver cultures as a physiological preclinical tool for hepatitis B virus infection
AM Ortega-Prieto, JK Skelton, SN Wai, E Large… - Nature …, 2018 - nature.com
With more than 240 million people infected, hepatitis B virus (HBV) is a major health
concern. The inability to mimic the complexity of the liver using cell lines and regular primary …
concern. The inability to mimic the complexity of the liver using cell lines and regular primary …