Skin tissue engineering—in vivo and in vitro applications
F Groeber, M Holeiter, M Hampel, S Hinderer… - Advanced drug delivery …, 2011 - Elsevier
Significant progress has been made over the years in the development of in vitro-
engineered substitutes that mimic human skin, either to be used as grafts for the …
engineered substitutes that mimic human skin, either to be used as grafts for the …
The human epidermal basement membrane: a shaped and cell instructive platform that aging slowly alters
E Roig-Rosello, P Rousselle - Biomolecules, 2020 - mdpi.com
One of the most important functions of skin is to act as a protective barrier. To fulfill this role,
the structural integrity of the skin depends on the dermal-epidermal junction—a complex …
the structural integrity of the skin depends on the dermal-epidermal junction—a complex …
Hydrogel dressings with intrinsic antibiofilm and antioxidative dual functionalities accelerate infected diabetic wound healing
Chronic wounds are often infected with biofilm bacteria and characterized by high oxidative
stress. Current dressings that promote chronic wound healing either require additional …
stress. Current dressings that promote chronic wound healing either require additional …
The pivotal role of vascularization in tissue engineering
Vascularization is one of the great challenges that tissue engineering faces in order to
achieve sizeable tissue and organ substitutes that contain living cells. There are instances …
achieve sizeable tissue and organ substitutes that contain living cells. There are instances …
Human in vitro skin models for wound healing and wound healing disorders
E Hofmann, J Fink, AL Pignet, A Schwarz… - Biomedicines, 2023 - mdpi.com
Skin wound healing is essential to health and survival. Consequently, high amounts of
research effort have been put into investigating the cellular and molecular components …
research effort have been put into investigating the cellular and molecular components …
Dermal fibroblast infiltration of poly (ε-caprolactone) scaffolds fabricated by melt electrospinning in a direct writing mode
Melt electrospinning in a direct writing mode is a recent additive manufacturing approach to
fabricate porous scaffolds for tissue engineering applications. In this study, we describe …
fabricate porous scaffolds for tissue engineering applications. In this study, we describe …
Design of hydrogel-based scaffolds for in vitro three-dimensional human skin model reconstruction
SH Tan, DAC Chua, JRJ Tang, C Bonnard… - Acta Biomaterialia, 2022 - Elsevier
In vitro three-dimensional (3D) skin tissue models are critical tools in advancing our
understanding of basic skin physiology and function as well as in specific applications such …
understanding of basic skin physiology and function as well as in specific applications such …
Skin tissue substitutes and biomaterial risk assessment and testing
Tremendous progress has been made over the past few decades to develop skin substitutes
for the management of acute and chronic wounds. With the advent of tissue engineering and …
for the management of acute and chronic wounds. With the advent of tissue engineering and …
Tissue engineered human skin equivalents
Z Zhang, BB Michniak-Kohn - Pharmaceutics, 2012 - mdpi.com
Human skin not only serves as an important barrier against the penetration of exogenous
substances into the body, but also provides a potential avenue for the transport of functional …
substances into the body, but also provides a potential avenue for the transport of functional …
Development of a Full-Thickness Human Skin Equivalent In Vitro Model Derived from TERT-Immortalized Keratinocytes and Fibroblasts
CMA Reijnders, A van Lier, S Roffel… - … Engineering Part A, 2015 - liebertpub.com
Currently, human skin equivalents (HSEs) used for in vitro assays (eg, for wound healing)
make use of primary human skin cells. Limitations of primary keratinocytes and fibroblasts …
make use of primary human skin cells. Limitations of primary keratinocytes and fibroblasts …