A review of ginsenosides from Panax ginseng in the treatment of inflammatory bowel disease

Z Niu, Y Liu, R Shen, X Jiang, Y Wang, Z He, J Li, Y Hu… - Phytomedicine, 2024 - Elsevier
Background Inflammatory bowel disease (IBD) is characterized by a chronic inflammation of
the intestine, which significantly affects patients' quality of life. As a perennial plant with the …

Protopanaxadiol triggers G0/G1 cell cycle arrest and apoptosis in human cervical cancer HeLa cells through the PPER pathway

R Lu, J Liu, K Thakur, H Cao, JC Mejuto… - Food Bioscience, 2024 - Elsevier
Protopanaxadiol (PPD) is considered to be the most active pharmacological element in
ginseng and has been widely studied for its anticancer effects. However, the detailed …

[HTML][HTML] Anti-inflammatory effects of the combined treatment of resveratrol-and protopanaxadiol-enriched rice seed extract on lipopolysaccharide-stimulated RAW264 …

C Monmai, SH Baek - Molecules, 2024 - mdpi.com
The overproduction of proinflammatory cytokines triggers a variety of diseases.
Protopanaxadiol (PPD) and resveratrol are naturally found in plants such as ginseng and …

Polygonatum cyrtonema saponin supplementation ameliorated DSS-induced intestinal barrier injury via targeting the PI3K/AKT/mTOR-mediated autophagy/microbiota …

J **ao, L **e, B Zheng, W Ma, Y Chen, J **e, X Hu… - Food Bioscience, 2024 - Elsevier
Autophagy is pivotal for the management of intestinal homeostasis, modulation of intestinal
immunity response and anti-microbial protection. Previous studies have documented the …

[HTML][HTML] Ginsenoside Rg1 regulated subpopulation homeostasis of Tfh cells ameliorate experimental colitis by inhibiting TLR/MyD88 pathway

Z Zhang, Q Jiang, L Huang, J Huang, Q Wan… - Journal of Functional …, 2024 - Elsevier
The imbalance of follicular helper T (Tfh) cell subset is closely related to the occurrence of
inflammatory bowel disease (IBD). Ginsenoside Rg1 (G-Rg1), the main component of …

Multi-omics reveal inhibitory effects of Protopanaxadiol on metastasis through PI3K-Akt and MAPK pathway in human cervical cancer HeLa cells

R Lu, J Liu, K Thakur, H Cao, JC Mejuto… - Food Bioscience, 2025 - Elsevier
Women are more prone to develop a risk of cervical cancer (CC), a cancer with a high
metastatic rate and unfavorable prognoses. Novel natural therapeutic agents are urgently …

[HTML][HTML] Ginsenoside Rg2, a principal effective ingredient of Panax ginseng, attenuates DSS-induced ulcerative colitis through NF-κB/NLRP3 pathway

J Zhang, J **e, Z Niu, L You, Y Liu, R Guo… - Journal of Ginseng …, 2025 - Elsevier
Abstract Background Ginsenoside Rg2 (G-Rg2), a major active compound of Panax
ginseng, exhibits a wide range of pharmacological properties, including anticancer …

Phenolics‐Rich Extract from Agarwood Leaf‐Tea Alleviate Dextran Sulfate Sodium (DSS)‐Induced Ulcerative Colitis Via Modulating Intestinal Barrier Function, Liver …

R Fan, W Wei, Y Wei, X Lin, S Zhou… - Molecular Nutrition & …, 2024 - Wiley Online Library
Scope At present, the incidence rate of ulcerative colitis (UC) continues to increase, causing
a global burden. In addition, therapeutic drugs have great side effects. According to modern …

Terpenoids from quinoa reverse chemoresistance in breast cancer by suppressing the stemness‐related lncRNA 667012

X Fan, M Feng, D Guo, S Li, Y An, J Tian, Z Li - Food Frontiers, 2025 - Wiley Online Library
Chemoresistance is a major cause of breast cancer (BC) recurrence and metastasis, and
chemotherapy resistance comes from tumor stemness. Our previous study showed that …