Modern mass spectrometry is one of the most frequently used methods of quantitative
proteomics, enabling determination of the amount of peptides in a sample. Although mass …

The inclusion of preliminary chemical labeling (derivatization) in the analysis process by
such powerful and widespread methods as electrospray ionization (ESI) and matrix-assisted …

No sensitive method for diagnosing early kidney dysfunction in horses has been identified
so far. Many studies carried out in humans and small animals show that podocin can be …

This work describes the development of a system that combines a derivatization protocol
based on the Katritzky reaction with paper spray ionization mass spectrometry (PSI-MS) for …

Pyrylium salts are considered efficient chemical tags for amino groups. However, the
apparent steric selectivity of pyrylium salts limits their application in the field of chemical …

The metabolomics and proteomics analysis of saliva, an excellent biofluid that is a rich
source of biological compounds, allows for the safe and frequent screening of drugs, their …

The lactosylation of whey proteins affects their properties, especially their allergenicity and
nutritional value, which matters in infant feeding. The quantification of lactosylated peptides …

Electrospray ionization mass spectrometry (ESI-MS) analysis is frequently associated with
noncovalent adduct formation, both in positive and negative modes. Anion binding and …

Detection of podocytes in urine might serve as a useful diagnostic tool in both primary and
secondary glomerular diseases. The utility of podocyturia has been confirmed for both pre …

Mass spectrometry methods are commonly used in the identification of peptides and
biomarkers. Due to a relatively low abundance of proteins in biological samples, there is a …