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Classification of current anticancer immunotherapies
During the past decades, anticancer immunotherapy has evolved from a promising
therapeutic option to a robust clinical reality. Many immunotherapeutic regimens are now …
therapeutic option to a robust clinical reality. Many immunotherapeutic regimens are now …
Silk-based delivery systems of bioactive molecules
Silks are biodegradable, biocompatible, self-assembling proteins that can also be tailored
via genetic engineering to contain specific chemical features, offering utility for drug and …
via genetic engineering to contain specific chemical features, offering utility for drug and …
Targeted delivery of proapoptotic peptides to tumor-associated macrophages improves survival
M Cieslewicz, J Tang, JL Yu, H Cao… - Proceedings of the …, 2013 - pnas.org
Most current cancer therapies focus on killing malignant cells, but these cells are often
genetically unstable and can become resistant to chemotherapy. Tumor-associated …
genetically unstable and can become resistant to chemotherapy. Tumor-associated …
Combinatorial peptide libraries: mining for cell-binding peptides
BP Gray, KC Brown - Chemical reviews, 2014 - ACS Publications
The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …
a unique cellular landscape specific to the type and state of the cell. Ligands that …
Oncolytic viruses in cancer therapy
MJV Vähä-Koskela, JE Heikkilä, AE Hinkkanen - Cancer letters, 2007 - Elsevier
Oncolytic virotherapy is a promising form of gene therapy for cancer, employing nature's own
agents to find and destroy malignant cells. The purpose of this review is to provide an …
agents to find and destroy malignant cells. The purpose of this review is to provide an …
Display technologies: application for the discovery of drug and gene delivery agents
A Sergeeva, MG Kolonin, JJ Molldrem… - Advanced drug delivery …, 2006 - Elsevier
Recognition of molecular diversity of cell surface proteomes in disease is essential for the
development of targeted therapies. Progress in targeted therapeutics requires establishing …
development of targeted therapies. Progress in targeted therapeutics requires establishing …
Trial Watch—Oncolytic viruses and cancer therapy
Oncolytic virotherapy relies on the administration of non-pathogenic viral strains that
selectively infect and kill malignant cells while favoring the elicitation of a therapeutically …
selectively infect and kill malignant cells while favoring the elicitation of a therapeutically …
Peptidic tumor targeting agents: the road from phage display peptide selections to clinical applications
KC Brown - Current pharmaceutical design, 2010 - benthamdirect.com
Cancer has become the number one cause of death amongst Americans, killing
approximately 1,600 people per day. Novel methods for early detection and the …
approximately 1,600 people per day. Novel methods for early detection and the …
Trial watch: oncolytic viruses for cancer therapy
Oncolytic viruses are natural or genetically modified viral species that selectively infect and
kill neoplastic cells. Such an innate or exogenously conferred specificity has generated …
kill neoplastic cells. Such an innate or exogenously conferred specificity has generated …
LyP-1-conjugated PEGylated liposomes: a carrier system for targeted therapy of lymphatic metastatic tumor
The application of liposomes in targeted therapy of lymphatic metastatic tumors has been
hampered by the low uptake rate of liposome by metastatic lymph nodes. In this report, LyP …
hampered by the low uptake rate of liposome by metastatic lymph nodes. In this report, LyP …