Classification of current anticancer immunotherapies

L Galluzzi, E Vacchelli, JM Bravo-San Pedro… - …, 2014 - pmc.ncbi.nlm.nih.gov
During the past decades, anticancer immunotherapy has evolved from a promising
therapeutic option to a robust clinical reality. Many immunotherapeutic regimens are now …

Silk-based delivery systems of bioactive molecules

K Numata, DL Kaplan - Advanced drug delivery reviews, 2010 - Elsevier
Silks are biodegradable, biocompatible, self-assembling proteins that can also be tailored
via genetic engineering to contain specific chemical features, offering utility for drug and …

Targeted delivery of proapoptotic peptides to tumor-associated macrophages improves survival

M Cieslewicz, J Tang, JL Yu, H Cao… - Proceedings of the …, 2013 - pnas.org
Most current cancer therapies focus on killing malignant cells, but these cells are often
genetically unstable and can become resistant to chemotherapy. Tumor-associated …

Combinatorial peptide libraries: mining for cell-binding peptides

BP Gray, KC Brown - Chemical reviews, 2014 - ACS Publications
The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …

Oncolytic viruses in cancer therapy

MJV Vähä-Koskela, JE Heikkilä, AE Hinkkanen - Cancer letters, 2007 - Elsevier
Oncolytic virotherapy is a promising form of gene therapy for cancer, employing nature's own
agents to find and destroy malignant cells. The purpose of this review is to provide an …

Display technologies: application for the discovery of drug and gene delivery agents

A Sergeeva, MG Kolonin, JJ Molldrem… - Advanced drug delivery …, 2006 - Elsevier
Recognition of molecular diversity of cell surface proteomes in disease is essential for the
development of targeted therapies. Progress in targeted therapeutics requires establishing …

Trial Watch—Oncolytic viruses and cancer therapy

J Pol, A Buqué, F Aranda, N Bloy, I Cremer… - …, 2016 - Taylor & Francis
Oncolytic virotherapy relies on the administration of non-pathogenic viral strains that
selectively infect and kill malignant cells while favoring the elicitation of a therapeutically …

Peptidic tumor targeting agents: the road from phage display peptide selections to clinical applications

KC Brown - Current pharmaceutical design, 2010 - benthamdirect.com
Cancer has become the number one cause of death amongst Americans, killing
approximately 1,600 people per day. Novel methods for early detection and the …

Trial watch: oncolytic viruses for cancer therapy

J Pol, N Bloy, F Obrist, A Eggermont, J Galon… - …, 2014 - Taylor & Francis
Oncolytic viruses are natural or genetically modified viral species that selectively infect and
kill neoplastic cells. Such an innate or exogenously conferred specificity has generated …

LyP-1-conjugated PEGylated liposomes: a carrier system for targeted therapy of lymphatic metastatic tumor

Z Yan, F Wang, Z Wen, C Zhan, L Feng, Y Liu… - Journal of controlled …, 2012 - Elsevier
The application of liposomes in targeted therapy of lymphatic metastatic tumors has been
hampered by the low uptake rate of liposome by metastatic lymph nodes. In this report, LyP …