The collagen suprafamily: from biosynthesis to advanced biomaterial development
Collagen is the oldest and most abundant extracellular matrix protein that has found many
applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview …
applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview …
Composition, structure and function of the corneal stroma
No other tissue in the body depends more on the composition and organization of the
extracellular matrix (ECM) for normal structure and function than the corneal stroma. The …
extracellular matrix (ECM) for normal structure and function than the corneal stroma. The …
Corneal repair and regeneration: current concepts and future directions
The cornea is a unique tissue and the most powerful focusing element of the eye, known as
a window to the eye. Infectious or non-infectious diseases might cause severe visual …
a window to the eye. Infectious or non-infectious diseases might cause severe visual …
Nearly-incompressible transverse isotropy (NITI) of cornea elasticity: model and experiments with acoustic micro-tap** OCE
The cornea provides the largest refractive power for the human visual system. Its stiffness,
along with intraocular pressure (IOP), are linked to several pathologies, including …
along with intraocular pressure (IOP), are linked to several pathologies, including …
Biomechanics of keratoconus: Two numerical studies
N Falgayrettes, E Patoor, F Cleymand, Y Zevering… - PloS one, 2023 - journals.plos.org
Background The steep cornea in keratoconus can greatly impair eyesight. The etiology of
keratoconus remains unclear but early injury that weakens the corneal stromal architecture …
keratoconus remains unclear but early injury that weakens the corneal stromal architecture …
Polarization microscopy for characterizing fiber orientation of ocular tissues
Characterizing the collagen fiber orientation and organization in the eye is necessary for a
complete understanding of ocular biomechanics. In this study, we assess the performance of …
complete understanding of ocular biomechanics. In this study, we assess the performance of …
Collagen architecture of the posterior pole: high-resolution wide field of view visualization and analysis using polarized light microscopy
Purpose: The purpose of this study was to leverage polarized light microscopy (PLM) to
visualize the collagen fiber architecture of posterior pole and optic nerve head with …
visualize the collagen fiber architecture of posterior pole and optic nerve head with …
A review of the epithelial and stromal effects of corneal collagen crosslinking
Induced corneal collagen crosslinking and mechanical stiffening via ultraviolet-A
photoactivation of riboflavin (UVA CXL) is now a common treatment for corneal ectasia and …
photoactivation of riboflavin (UVA CXL) is now a common treatment for corneal ectasia and …
Quantitative structural imaging of keratoconic corneas using polarization-resolved SHG microscopy
C Raoux, M Schmeltz, M Bied, M Alnawaiseh… - Biomedical optics …, 2021 - opg.optica.org
The human cornea is mainly composed of collagen fibrils aligned together within stacked
lamellae. This lamellar structure can be affected in pathologies such as keratoconus, which …
lamellae. This lamellar structure can be affected in pathologies such as keratoconus, which …
Finite element modeling of the complex anisotropic mechanical behavior of the human sclera and pia mater
Background and objective Accurate finite element (FE) simulation of the optic nerve head
(ONH) depends on accurate mechanical properties of the load-bearing tissues. The …
(ONH) depends on accurate mechanical properties of the load-bearing tissues. The …