Crosstalk between gut microbiota and host immunity: impact on inflammation and immunotherapy

C Campbell, MR Kandalgaonkar, RM Golonka… - Biomedicines, 2023 - mdpi.com
Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …

Immunomodulatory biomaterials against bacterial infections: Progress, challenges, and future perspectives

S Zhang, H Yang, M Wang, D Mantovani, K Yang… - The Innovation, 2023 - cell.com
Bacterial infectious diseases are one of the leading causes of death worldwide. Even with
the use of multiple antibiotic treatment strategies, 4.95 million people died from drug …

Neurovascular coupling impairment as a mechanism for cognitive deficits in COVID-19

CD Owens, C Bonin Pinto, S Detwiler… - Brain …, 2024 - academic.oup.com
Components that comprise our brain parenchymal and cerebrovascular structures provide a
homeostatic environment for proper neuronal function to ensure normal cognition. Cerebral …

[HTML][HTML] Neutrophils' extracellular trap mechanisms: from physiology to pathology

J Schoen, M Euler, C Schauer, G Schett… - International Journal of …, 2022 - mdpi.com
Neutrophils are an essential part of the innate immune system and the first line of defense
against invading pathogens. They phagocytose, release granular contents, produce reactive …

COVID-19 vaccination in patients with malignancy; a systematic review and meta-analysis of the efficacy and safety

SA Javadinia, K Alizadeh, MS Mojadadi… - Frontiers in …, 2022 - frontiersin.org
Background Data on the efficacy and safety of COVID-19 vaccines in patients with
malignancy are immature. In this paper, we assessed the literature involving the use of …

Cytokine storm and translating IL-6 biology into effective treatments for COVID-19

T Li, D Wang, H Wei, X Xu - Frontiers of Medicine, 2023 - Springer
Abstract As of May 3, 2023, the Coronavirus disease 2019 (COVID-19) pandemic has
resulted in more than 760 million confirmed cases and over 6.9 million deaths. Several …

RIPK1 inhibitor ameliorates pulmonary injury by modulating the function of neutrophils and vascular endothelial cells

T Yang, C **ang, X Wang, Q Li, S Lei, K Zhang… - Cell Death …, 2024 - nature.com
Acute lung injury (ALI) is an acute and progressive hypoxic respiratory failure that could
progress to acute respiratory distress syndrome (ARDS) with a high mortality rate, thus …

[HTML][HTML] Phenotypes and functions of “aged” neutrophils in cardiovascular diseases

S Ling, JW Xu - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Neutrophils are important effector cells of innate immunity and undergo several phenotypic
changes after release from the bone marrow. Neutrophils with a late life cycle phenotype are …

Platelet-neutrophil interaction in COVID-19 and vaccine-induced thrombotic thrombocytopenia

J Hirsch, G Uzun, J Zlamal, A Singh… - Frontiers in …, 2023 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is known to commonly induce a thrombotic diathesis,
particularly in severely affected individuals. So far, this COVID-19-associated coagulopathy …

Sustained viral suppression with dolutegravir monotherapy over 192 weeks in patients starting combination antiretroviral therapy during primary human …

E West, M Zeeb, C Grube, H Kuster… - Clinical Infectious …, 2023 - academic.oup.com
Background Starting combination antiretroviral therapy (cART) during primary human
immunodeficiency virus type 1 (HIV-1) infection results in a smaller HIV-1 latent reservoir …