The burden of neurologic diseases, including stroke and dementia, is expected to grow
substantially in the coming decades. Thus, achieving optimal brain health has been …

Although substantial progress has been made in reducing the burden of the disease by
preventing the risk factors of cardiovascular disease (CVD), potential risk factors still exist …

Astrocytes provide crucial support for neurons, contributing to synaptogenesis, synaptic
maintenance, and neurotransmitter recycling. Under pathological conditions, deregulation of …

Objective Accumulating evidence shows that cognitive impairment (CI) in chronic heart
failure (CHF) patients is related to brain network dysfunction. This study investigated brain …

Background Given the increased risk of chronic diseases and comorbidity among middle-
aged and older adults in China, it is pivotal to identify the disease trajectory of develo** …

MicroRNAs have been linked to synaptic plasticity and memory function and are emerging
as potential biomarkers and therapeutic targets for cognitive diseases. Most of these data …

Aims This systematic review aimed to study the hippocampal and frontal changes of heart
failure (HF) patients and HF animal models with cognitive impairment or depression …

In mammals, histone 3 lysine 4 methylation (H3K4me) is mediated by six different lysine
methyltransferases. Among these enzymes, SETD1B (SET domain containing 1b) has been …

Introduction Heart Failure and Cognitive Impairment are both on the rise and shown to be
interlinked. Despite existing reviews delineating a relationship between heart failure and …

Abstract Purpose of Review There is increasing recognition of the prevalence and impact of
cognitive dysfunction (CD) in heart failure (HF) patients. This contemporary review appraises …