Web-based multi-omics integration using the analyst software suite

JD Ewald, G Zhou, Y Lu, J Kolic, C Ellis, JD Johnson… - Nature …, 2024 - nature.com
The growing number of multi-omics studies demands clear conceptual workflows coupled
with easy-to-use software tools to facilitate data analysis and interpretation. This protocol …

Microplastic-associated pathogens and antimicrobial resistance in environment

K Kaur, S Reddy, P Barathe, U Oak, V Shriram… - Chemosphere, 2022 - Elsevier
The ubiquitous use of microplastics and their release into the environment especially the
water bodies by anthropogenic/industrial activities are the major resources for microplastic …

Spontaneous immortalization of chicken fibroblasts generates stable, high-yield cell lines for serum-free production of cultured meat

L Pasitka, M Cohen, A Ehrlich, B Gildor, E Reuveni… - Nature Food, 2023 - nature.com
Cellular agriculture could meet growing demand for animal products, but yields are typically
low and regulatory bodies restrict genetic modification for cultured meat production. Here we …

Molecular and network-level mechanisms explaining individual differences in autism spectrum disorder

AM Buch, PE Vértes, J Seidlitz, SH Kim… - Nature …, 2023 - nature.com
The mechanisms underlying phenotypic heterogeneity in autism spectrum disorder (ASD)
are not well understood. Using a large neuroimaging dataset, we identified three latent …

NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis

G Zhou, O Soufan, J Ewald, REW Hancock… - Nucleic acids …, 2019 - academic.oup.com
The growing application of gene expression profiling demands powerful yet user-friendly
bioinformatics tools to support systems-level data understanding. NetworkAnalyst was first …

MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis

J Chong, O Soufan, C Li, I Caraus, S Li… - Nucleic acids …, 2018 - academic.oup.com
We present a new update to MetaboAnalyst (version 4.0) for comprehensive metabolomic
data analysis, interpretation, and integration with other omics data. Since the last major …

Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice

HH Pak, SA Haws, CL Green, M Koller… - Nature …, 2021 - nature.com
Calorie restriction (CR) promotes healthy ageing in diverse species. Recently, it has been
shown that fasting for a portion of each day has metabolic benefits and promotes lifespan …

[PDF][PDF] MicrobiomeAnalyst: a web-based tool for comprehensive statistical, visual and meta-analysis of microbiome data

A Dhariwal, J Chong, S Habib, IL King… - Nucleic acids …, 2017 - academic.oup.com
The widespread application of next-generation sequencing technologies has revolutionized
microbiome research by enabling high-throughput profiling of the genetic contents of …

The immunology of host defence peptides: beyond antimicrobial activity

REW Hancock, EF Haney, EE Gill - Nature Reviews Immunology, 2016 - nature.com
Host defence peptides (HDPs) are short, cationic amphipathic peptides with diverse
sequences that are produced by various cells and tissues in all complex life forms. HDPs …

Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease

A Boza-Serrano, R Ruiz, R Sanchez-Varo… - Acta …, 2019 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disease in which the
formation of extracellular aggregates of amyloid beta (Aβ) peptide, fibrillary tangles of …