Role of spectral counting in quantitative proteomics

DH Lundgren, SI Hwang, L Wu… - Expert review of …, 2010 - Taylor & Francis
Spectral count, defined as the total number of spectra identified for a protein, has gained
acceptance as a practical, label-free, semiquantitative measure of protein abundance in …

Simple, efficient and thorough shotgun proteomic analysis with PatternLab V

MDM Santos, DB Lima, JSG Fischer, MA Clasen… - Nature protocols, 2022 - nature.com
Shotgun proteomics aims to identify and quantify the thousands of proteins in complex
mixtures such as cell and tissue lysates and biological fluids. This approach uses liquid …

[HTML][HTML] The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon

DR Donohoe, N Garge, X Zhang, W Sun, TM O'Connell… - Cell metabolism, 2011 - cell.com
The microbiome is being characterized by large-scale sequencing efforts, yet it is not known
whether it regulates host metabolism in a general versus tissue-specific manner or which …

eulerAPE: Drawing Area-Proportional 3-Venn Diagrams Using Ellipses

L Micallef, P Rodgers - PloS one, 2014 - journals.plos.org
Venn diagrams with three curves are used extensively in various medical and scientific
disciplines to visualize relationships between data sets and facilitate data analysis. The area …

A deeper look into Comet—implementation and features

JK Eng, MR Hoopmann, TA Jahan… - Journal of the …, 2015 - ACS Publications
The Comet database search software was initially released as an open source project in late
2012. Prior to that, Comet existed as the University of Washington's academic version of the …

Integrated analysis of shotgun proteomic data with PatternLab for proteomics 4.0

PC Carvalho, DB Lima, FV Leprevost, MDM Santos… - Nature protocols, 2016 - nature.com
PatternLab for proteomics is an integrated computational environment that unifies several
previously published modules for the analysis of shotgun proteomic data. The contained …

Current trends in quantitative proteomics

MH Elliott, DS Smith, CE Parker… - Journal of Mass …, 2009 - Wiley Online Library
It was inevitable that as soon as mass spectrometrists were able to tell biologists which
proteins were in their samples, the next question would be how much of these proteins were …

Post-production modifications of murine mesenchymal stem cell (mMSC) derived extracellular vesicles (EVs) and impact on their cellular interaction

S Le Saux, H Aarrass, J Lai-Kee-Him, P Bron… - Biomaterials, 2020 - Elsevier
In regards to their key role in intercellular communication, extracellular vesicles (EVs) have a
strong potential as bio-inspired drug delivery systems (DDS). With the aim of circumventing …

Proteomics in forensic analysis: Applications for human samples

VA Duong, JM Park, HJ Lim, H Lee - Applied Sciences, 2021 - mdpi.com
Proteomics, the large-scale study of all proteins of an organism or system, is a powerful tool
for studying biological systems. It can provide a holistic view of the physiological and …

Proteome analysis of the surface of Trichomonas vaginalis reveals novel proteins and strain-dependent differential expression

N de Miguel, G Lustig, O Twu, A Chattopadhyay… - Molecular & Cellular …, 2010 - ASBMB
The identification of surface proteins on the plasma membrane of pathogens is of
fundamental importance in understanding host-pathogen interactions. Surface proteins of …