Thymomas are considered one of the most prevalent types of mediastinal epithelial tumors,
which frequently develop in the anterior mediastinum. Due to their rarity, these tumors' …

The epithelial and lymphoid compartments of the thymus can give rise to a wide variety of
tumours, including thymomas, thymic carcinomas, lymphoreticular proliferations, germ cell …

Pax8 is a transcription factor associated with the embryonic development of the thyroid
gland, kidney, and the Müllerian system and plays a role in the tumorigenesis of these …

Thymomas exhibit a unique genomic landscape, comprising the lowest on average total
mutational burden among adult human cancers; a unique point mutation in the GTF2I gene …

PAX8 is expressed in thymic epithelial neoplasms and a subset of neuroendocrine
carcinomas of gastrointestinal origin but not pulmonary neuroendocrine carcinomas. Thyroid …

Myasthenia gravis (MG) is an autoantibody mediated autoimmune disease characterized by
skeletal muscle fatigability and weakness through different types of immune attacks against …

The diagnosis of thymic epithelial neoplasms is normally rendered after careful evaluation of
their histologic features. In some cases, however, the morphological heterogeneity or …

The expression of immunohistochemical markers has been extensively investigated in
thymomas to assist in the differential diagnosis. We have studied six select markers to …

Spindle cell thymomas are a subset of thymoma that is characterized by great morphologic
variability. This histologic complexity coupled with the overall rarity of these lesions can …

Objectives: Neuroendocrine differentiation in carcinomas of the nonneuroendocrine type
has been observed in various organ systems. Awareness of this phenomenon is important …