Cyclodextrins in peptide and protein delivery

T Irie, K Uekama - Advanced Drug Delivery Reviews, 1999 - Elsevier
The objective of this contribution is to summarize recent findings on the potential of
cyclodextrins (CDs) and their derivatives as carriers for therapeutically important peptides …

Nasal bioavailability of peptide T in rabbits: absorption enhancement by sodium glycocholate and glycofurol

MA Bagger, HW Nielsen, E Bechgaard - European journal of …, 2001 - Elsevier
The aim of the present study was to investigate the absolute nasal bioavailability of Peptide
T from aqueous formulations containing sodium glycocholate, an absorption enhancer with …

Design and in vivo evaluation of solid-in-oil suspension for oral delivery of human growth hormone

H Yoshiura, Y Tahara, M Hashida, N Kamiya… - Biochemical …, 2008 - Elsevier
Solid-in-oil (S/O) suspension containing human growth hormone (hGH), in which hGH was
complexed with an edible surfactant, was designed and validated for oral administration of …

Alkanoylsucroses in nasal delivery of low molecular weight heparins: in-vivo absorption and reversibility studies in rats

T Yang, F Mustafa, F Ahsan - Journal of pharmacy and …, 2004 - academic.oup.com
The efficacy of alkanoylsucroses in enhancing nasal absorption of low molecular weight
heparin (LMWH) and the time span of action of these agents on the nasal membrane has …

Determination of human growth hormone in pure and pharmaceutical dosage form by spectrofluorometry and high performance liquid chromatography

B Yilmaz, Y Kadioglu, K Meral… - Chemical Industry and …, 2012 - doiserbia.nb.rs
In this study, a new and rapid spectrofluorometry and high performance liquid
chromatography (HPLC) methods were developed for determination of human growth …

Shape changes in the erythrocyte membrane induced by the absorption enhancer didecanoylphosphatidylcholine

C Vermehren, HS Hansen - International journal of pharmaceutics, 1998 - Elsevier
The phospholipid didecanoylphosphatidylcholine (DDPC) has been shown to promote the
nasal absorption of peptide drugs in rabbits. The absorption enhancing effect has been …

Reversibility and clinical relevance of morphological changes after nasal application of ephedrine nasal drops 1%

E Bechgaard, E Bindseil, M Bagger… - International journal of …, 1997 - Elsevier
To predict the toxicity of nasal formulations, various in vitro and in vivo techniques have
been used. Many of these techniques are very sensitive and it is a general problem to …

[PDF][PDF] Nasal delivery of peptide and nonpeptide drugs

C Thomas, F Ahsan - Pharmaceutical manufacturing handbook …, 2008 - academia.edu
Nasal delivery of peptide and nonpeptide drugs Page 607 591 5.6 NASAL DELIVERY OF
PEPTIDE AND NONPEPTIDE DRUGS Chandan Thomas and Fakhrul Ahsan Texas Tech …

Effectiveness of Pirotiodecane, Absorption Enhancer, on Nasal Absorption in Rabbits

H Otake, M Tomita, M Sugimoto, Y Idota… - Drug metabolism and …, 2005 - Elsevier
The absorption enhancing effect of 1-[2-(decylthio) ethyl] azacyclopentan-2-one
(Pirotiodecane), on drug permeation across rabbit nasal mucosa was studied. The nasal …

[CITATION][C] Cyclodextrin‐Enhanced Drug Delivery through Mucous Membranes

P Jansook, ME Brewster… - Cyclodextrins …, 2011 - John Wiley & Sons, Inc. Hoboken …