Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Peptide design principles for antimicrobial applications

MDT Torres, S Sothiselvam, TK Lu… - Journal of molecular …, 2019 - Elsevier
The increased incidence of bacterial resistance to available antibiotics represents a major
global health problem and highlights the need for novel anti-infective therapies …

Treatment of Superbug Infection through a Membrane‐Disruption and Immune‐Regulation Cascade Effect Based on Supramolecular Peptide Hydrogels

Y Liu, H Gong, Z Wang, C Yuan, J Lu… - Advanced Functional …, 2023 - Wiley Online Library
Infections from antimicrobial resistant pathogens have been considered as lethal threats to
human health if antibiotic treatments become ineffective. Antimicrobial peptides (AMPs) …

[HTML][HTML] From oncolytic peptides to oncolytic polymers: A new paradigm for oncotherapy

H Liu, W Shen, W Liu, Z Yang, D Yin, C **ao - Bioactive Materials, 2024 - Elsevier
Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …

ACPred: a computational tool for the prediction and analysis of anticancer peptides

N Schaduangrat, C Nantasenamat, V Prachayasittikul… - Molecules, 2019 - mdpi.com
Anticancer peptides (ACPs) have emerged as a new class of therapeutic agent for cancer
treatment due to their lower toxicity as well as greater efficacy, selectivity and specificity …

Low molecular weight self-assembling peptide-based materials for cell culture, antimicrobial, anti-inflammatory, wound healing, anticancer, drug delivery, bioimaging …

AK Das, PK Gavel - Soft Matter, 2020 - pubs.rsc.org
In this review, we have focused on the design and development of low molecular weight self-
assembling peptide-based materials for various applications including cell proliferation …

Rational Design and Synthesis of Lignin‐Derived Smart Sunscreens

Y Wu, X Wu, A Zhang, X Ouyang, H Lou… - Advanced Functional …, 2023 - Wiley Online Library
Lignin exhibits a long‐active UV‐blocking property due to its macromolecular aromatic
structure and unique semiquione‐quione‐hydroquione transition. However, its poor …

Improved prediction and characterization of anticancer activities of peptides using a novel flexible scoring card method

P Charoenkwan, W Chiangjong, VS Lee… - Scientific reports, 2021 - nature.com
As anticancer peptides (ACPs) have attracted great interest for cancer treatment, several
approaches based on machine learning have been proposed for ACP identification …

[HTML][HTML] Rationally designed short cationic α-helical peptides with selective anticancer activity

R Hadianamrei, MA Tomeh, S Brown, J Wang… - Journal of Colloid and …, 2022 - Elsevier
Hypothesis Naturally derived or synthetic anticancer peptides (ACPs) have emerged as a
new generation of anticancer agents with higher selectivity for cancer cells and less …

Hydrophobic control of the bioactivity and cytotoxicity of de novo-designed antimicrobial peptides

H Gong, J Zhang, X Hu, Z Li, K Fa, H Liu… - … applied materials & …, 2019 - ACS Publications
Antimicrobial peptides (AMPs) can target bacterial membranes and kill bacteria through
membrane structural damage and cytoplasmic leakage. A group of surfactant-like cationic …