Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …

Cerebral malaria (CM), results from Plasmodium falciparum infection, and has a high
mortality rate. CM survivors can retain life-long post CM sequelae, including seizures and …

Plasmodium falciparum causes the most severe and fatal form of malaria in humans with
over half a million deaths each year. Cerebral malaria, a complex neurological syndrome of …

Sequestration of Plasmodium falciparum‐infected erythrocytes (IE) within the brain
microvasculature is a hallmark of cerebral malaria (CM). Using a microchannel flow …

Systemic inflammation mediated by Plasmodium parasites is central to malaria disease and
its complications. Plasmodium parasites reside in erythrocytes and can theoretically reach …

Selective modulation of autophagy is a promising therapeutic strategy, especially for cancer
treatment. However, the lack of specific autophagy inhibitors limits this strategy. The …

Severe malaria due to Plasmodium falciparum infection causes nearly half a million deaths
per year. The different symptomatology and disease manifestations among patients have …

By attaching infected erythrocytes to the vascular lining, Plasmodium falciparum parasites
leave blood circulation and avoid splenic clearance. This sequestration is central to …

The impact of cerebral malaria on the transcriptional profiles of cerebral tissues is difficult to
study using noninvasive approaches. We isolated plasma extracellular vesicles (EVs) from …

L-asparaginase has been used for more than three decades in acute lymphoblastic
leukemia (ALL) patients and remains an essential drug in the treatment of ALL. Poor …