Mechanisms and clinical relevance of bacterial heteroresistance

DI Andersson, H Nicoloff, K Hjort - Nature Reviews Microbiology, 2019 - nature.com
Antibiotic heteroresistance is a phenotype in which a bacterial isolate contains
subpopulations of cells that show a substantial reduction in antibiotic susceptibility …

Fosfomycin

ME Falagas, EK Vouloumanou… - Clinical microbiology …, 2016 - Am Soc Microbiol
The treatment of bacterial infections suffers from two major problems: spread of multidrug-
resistant (MDR) or extensively drug-resistant (XDR) pathogens and lack of development of …

Fosfomycin: mechanism and resistance

LL Silver - Cold Spring Harbor perspectives in …, 2017 - perspectivesinmedicine.cshlp.org
Fosfomycin, a natural product antibiotic, has been in use for> 20 years in Spain, Germany,
France, Japan, Brazil, and South Africa for urinary tract infections (UTIs) and other …

Pandrug-resistant Gram-negative bacteria: a systematic review of current epidemiology, prognosis and treatment options

S Karakonstantis, EI Kritsotakis… - Journal of Antimicrobial …, 2020 - academic.oup.com
Background The literature on the epidemiology, mortality and treatment of pandrug-resistant
(PDR) Gram-negative bacteria (GNB) is scarce, scattered and controversial. Objectives To …

Resistance to fosfomycin: mechanisms, frequency and clinical consequences

ME Falagas, F Athanasaki, GL Voulgaris… - International journal of …, 2019 - Elsevier
Fosfomycin has been used for the treatment of infections due to susceptible and multidrug-
resistant (MDR) bacteria. It inhibits bacterial cell wall synthesis through a unique mechanism …

[HTML][HTML] Antibiotic selection in the treatment of acute invasive infections by Pseudomonas aeruginosa: Guidelines by the Spanish Society of Chemotherapy

J Mensa, J Barberán, A Soriano, P Llinares… - Revista Española de …, 2018 - ncbi.nlm.nih.gov
Pseudomonas aeruginosa is characterized by a notable intrinsic resistance to antibiotics,
mainly mediated by the expression of inducible chromosomic β-lactamases and the …

Emerging Gram negative resistance to last-line antimicrobial agents fosfomycin, colistin and ceftazidime-avibactam–epidemiology, laboratory detection and treatment …

N Sherry, B Howden - Expert review of anti-infective therapy, 2018 - Taylor & Francis
ABSTRACT Introduction: Multidrug-resistant (MDR) and extensively-drug-resistant (XDR)
Gram-negative bacteria have emerged as a major threat to human health globally. This has …

Prevalence of antibiotic resistance of Pseudomonas aeruginosa in cystic fibrosis infection: A systematic review and meta-analysis

P Bonyadi, NT Saleh, M Dehghani, M Yamini… - Microbial …, 2022 - Elsevier
Objective Pseudomonas aeruginosa is an opportunistic pathogen that infects the lungs of
people with cystic fibrosis (CF) and is the most common cause of chronic respiratory …